Targeting ErbB3 and Cellular NADPH/NADP+ Abundance Sensitizes Cutaneous Melanomas to Ferroptosis Inducers.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00113
Abstract: Melanoma is a serious health challenge. Ferroptosis is a regulated form of oxidative cell death that shows varied efficacy in melanoma. We aimed to better understand the molecular basis for this differential ferroptosis sensitivity. We… read more here.
Keywords: erbb3; ferroptosis inducers; nadph nadp; targeting erbb3 ... See more keywords
Genetically encoded ATP and NAD(P)H biosensors: potential tools in metabolic engineering.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in biotechnology"
DOI: 10.1080/07388551.2022.2103394
Abstract: To date, many metabolic engineering tools and strategies have been developed, including tools for cofactor engineering, which is a common strategy for bioproduct synthesis. Cofactor engineering is used for the regulation of pyridine nucleotides, including… read more here.
Keywords: metabolic engineering; nadh nad; nad nadph; cofactor ... See more keywords