Role of PLD−PKCζ signaling axis in p47phox phosphorylation for activation of NADPH oxidase by angiotensin II in pulmonary artery smooth muscle cells
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11145
Abstract: We sought to determine the mechanism by which angiotensin II (ANGII) stimulates NADPH oxidase‐mediated superoxide (O2.−) production in bovine pulmonary artery smooth muscle cells (BPASMCs). ANGII‐induced increase in phospholipase D (PLD) and NADPH oxidase activities… read more here.
Keywords: oxidase; pkc; pld; angii induced ... See more keywords
Renoprotective effect of vinpocetine against ischemia/reperfusion injury: Modulation of NADPH oxidase/Nrf2, IKKβ/NF‐κB p65, and cleaved caspase‐3 expressions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23046
Abstract: Ischemia/reperfusion injury (IRI) during kidney transplantation is a serious clinical problem with a high mortality rate and a lack of therapy. Therefore, there is a need to improve the ability of the kidney to tolerate… read more here.
Keywords: ikk p65; effect vinpocetine; nadph oxidase; vinpocetine ... See more keywords
NADPH oxidase 4 regulate the glycolytic metabolic reprogramming of microglial cells to promote M1 polarization
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23318
Abstract: This work aimed to investigate the role and mechanism of NADPH oxidase 4 (NOX4) in the polarization of microglial cells. Microglial cells were transfected with the NOX4 overexpression plasmid (pGL3‐NOX4), and later treated with lipopolysaccharide… read more here.
Keywords: nadph oxidase; microglial cells; expression; polarization ... See more keywords
Measurement of Superoxide Production and NADPH Oxidase Activity by HPLC Analysis of Dihydroethidium Oxidation.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6625-7_19
Abstract: The fluorogenic probe dihydroethidium (DHE) is widely used for detecting intracellular superoxide. DHE oxidation by superoxide generates specifically the compound 2-hydroxyethidium (2-E+OH), so that 2-E+OH detection confers specificity to superoxide assessment among many other reactive… read more here.
Keywords: hplc; oxidation; dihydroethidium; superoxide ... See more keywords
Using Synthetic Peptides for Exploring Protein-Protein Interactions in the Assembly of the NADPH Oxidase Complex.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9424-3_23
Abstract: The NADPH oxidase complex, responsible for reactive oxygen species (ROS) generation by phagocytes, consists of a membrane-associated flavocytochrome b 558 (a heterodimer of NOX2 and p22phox) and the cytosolic components p47phox, p67phox, Rac(1 or 2),… read more here.
Keywords: protein; oxidase; component; protein protein ... See more keywords
Arachidonic Acid and Nitroarachidonic: Effects on NADPH Oxidase Activity.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-11488-6_6
Abstract: Arachidonic acid (AA) is a polyunsaturated fatty acid that participates in the inflammatory response mainly through bioactive-lipids formation in macrophages and also in the phagocytic NADPH oxidase 2 (NOX2) activation. NOX2 is the enzyme responsible… read more here.
Keywords: formation; arachidonic acid; nadph oxidase; acid ... See more keywords
Apocynin ameliorates NADPH oxidase 4 (NOX4) induced oxidative damage in the hypoxic human retinal Müller cells and diabetic rat retina.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04071-y
Abstract: NADPH oxidase (NOX) is a main producers of reactive oxygen species (ROS) that may contribute to the early pathogenesis of diabetic retinopathy (DR). ROS has harmful effects on endogenous neuro-survival factors brain-derived neurotrophic factor (BDNF)… read more here.
Keywords: human retinal; nox4 induced; bdnf sirt1; nadph oxidase ... See more keywords
Graft-transmissible resistance of cherry pepper (Capsicum annuum var. cerasiforme) to powdery mildew (Leveillula taurica) is associated with elevated superoxide accumulation, NADPH oxidase activity and pathogenesis-related gene expression
Sign Up to like & getrecommendations! Published in 2017 at "Acta Physiologiae Plantarum"
DOI: 10.1007/s11738-017-2353-5
Abstract: We found that resistance to pepper powdery mildew (PM) (Leveillula taurica) develops in a sweet pepper (Capsicum annuum) cultivar (‘Totál’) when grafted on a resistant cherry pepper (C. annuum var. cerasiforme) rootstock (cv. Szentesi). Resistance… read more here.
Keywords: accumulation; graft transmissible; expression; resistance ... See more keywords
Differential expression of NADPH oxidase-2 (Nox-2) and nuclear factor-erythroid 2-related factor 2 (Nrf2) transcripts in peripheral blood mononuclear cells isolated from dengue patients
Sign Up to like & getrecommendations! Published in 2017 at "VirusDisease"
DOI: 10.1007/s13337-017-0365-9
Abstract: Abstract The role of oxidative stress in the pathogenesis of dengue infection is not completely known. A recent study reveals the involvement of oxidative stress responsive molecules in the generation of host immune responses to… read more here.
Keywords: study; blood; dengue; nadph oxidase ... See more keywords
Maternal endotoxemia induces renal collagen deposition in adult offspring: Role of NADPH oxidase/TGF-β1/MMP-2 signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108306
Abstract: Maternal endotoxemia has been shown to increase renal collagen deposition in the offspring. Renal fibrosis is a hallmark of progressive chronic kidney disease. It was investigated whether maternal reactive oxygen species (ROS) leads to renal… read more here.
Keywords: collagen; collagen deposition; maternal endotoxemia; adult offspring ... See more keywords
FTY720 induces neutrophil extracellular traps via a NADPH oxidase-independent pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.109015
Abstract: FTY720 is an immunosuppressive agent which has been approved to treat multiple sclerosis (MS). The main object of the present study is to investigate whether FTY720 has the potential to induce the formation of neutrophil… read more here.
Keywords: neutrophil extracellular; fty720; formation; nadph oxidase ... See more keywords