Insights into the NOX NADPH Oxidases Using Heterologous Whole Cell Assays.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9424-3_9
Abstract: Assays based on ectopic expression of NOX NADPH oxidase subunits in heterologous mammalian cells are an important approach for investigating features of this family of enzymes. These model systems have been used to analyze the… read more here.
Keywords: whole cell; heterologous whole; nadph oxidases; nox nadph ... See more keywords
Structural complexity and functional diversity of plant NADPH oxidases
Sign Up to like & getrecommendations! Published in 2017 at "Amino Acids"
DOI: 10.1007/s00726-017-2491-5
Abstract: Plant NADPH oxidases also known as respiratory burst oxidase homologs (Rbohs) are a family of membrane-bound enzymes that play diverse roles in the defense response and morphogenetic processes via regulated generation of reactive oxygen species.… read more here.
Keywords: functional diversity; plant nadph; plant; nadph oxidases ... See more keywords
NADPH oxidases: Pathophysiology and therapeutic potential in age-associated pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101541
Abstract: Oxidative stress has been associated with a number of human fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). Although oxidative stress is associated with both fibrosis and aging, the precise cellular sources(s) of reactive oxygen species… read more here.
Keywords: fibrosis; oxidases pathophysiology; nadph oxidases; pulmonary fibrosis ... See more keywords
NADPH Oxidases in the differentiation of endothelial cells.
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular research"
DOI: 10.1093/cvr/cvz213
Abstract: The differentiation of stem cells into endothelial cells involves the modulation of highly interconnected metabolic and epigenetic processes. Therefore, the differentiation of endothelial cells is a tightly controlled process, which is adjusted at multiple levels,… read more here.
Keywords: nadph oxidases; differentiation stem; endothelial cells; differentiation endothelial ... See more keywords
THU0093 Nadph oxidases associated production of reactive oxygen species in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6702
Abstract: Background Reactive oxygen species (ROS) is produced during metabolism of Oxygen. ROS is important in cell signalling and homeostasis. Production of ROS can be elevated in stressful condition. Oxidative stress has been known to be… read more here.
Keywords: reactive oxygen; production; rheumatoid arthritis; nadph oxidases ... See more keywords
Role of NADPH Oxidases in Renal Aging.
Sign Up to like & getrecommendations! Published in 2023 at "Gerontology"
DOI: 10.1159/000529392
Abstract: INTRODUCTION Aging of the kidney is associated with complex molecular, histological, and functional changes. Although the aging process itself does not induce renal damage, underlying disease such as diabetes mellitus can aggravate kidney injury during… read more here.
Keywords: nadph oxidases; age; oxidative stress; mice ... See more keywords
Activity-regulated growth of motoneurons at the neuromuscular junction is mediated by NADPH oxidases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1106593
Abstract: Neurons respond to changes in the levels of activity they experience in a variety of ways, including structural changes at pre- and postsynaptic terminals. An essential plasticity signal required for such activity-regulated structural adjustments are… read more here.
Keywords: neuromuscular junction; activity regulated; growth; activity ... See more keywords
Yin and Yang of NADPH Oxidases in Myocardial Ischemia-Reperfusion
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DOI: 10.3390/antiox11061069
Abstract: Oxidative stress is critically involved in the pathophysiology of myocardial ischemic-reperfusion (I/R) injury. NADPH oxidase (Nox) 2 and 4, major sources of reactive oxygen species (ROS) in cardiomyocytes, are upregulated in response to I/R. Suppression… read more here.
Keywords: oxidases myocardial; reperfusion; myocardial ischemia; yin yang ... See more keywords
NADPH Oxidases in Diastolic Dysfunction and Heart Failure with Preserved Ejection Fraction
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DOI: 10.3390/antiox11091822
Abstract: Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases regulate production of reactive oxygen species (ROS) that cause oxidative damage to cellular components but also regulate redox signaling in many cell types with essential functions in the cardiovascular… read more here.
Keywords: nadph oxidases; heart failure; heart; diastolic dysfunction ... See more keywords
NADPH Oxidases in Aortic Aneurysms
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DOI: 10.3390/antiox11091830
Abstract: Abdominal aortic aneurysms (AAAs) are a progressive dilation of the infrarenal aorta and are characterized by inflammatory cell infiltration, smooth muscle cell migration and proliferation, and degradation of the extracellular matrix. Oxidative stress and the… read more here.
Keywords: aortic aneurysms; cell; oxidases aortic; aaas ... See more keywords
Role of NADPH Oxidases in Blood–Brain Barrier Disruption and Ischemic Stroke
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DOI: 10.3390/antiox11101966
Abstract: NADPH oxidases (Nox) are one of the main sources of reactive oxygen species (ROS) in the central nervous system (CNS). While these enzymes have been shown to be involved in physiological regulation of cerebral vascular… read more here.
Keywords: role; blood brain; brain barrier; brain ... See more keywords