A case of primary amebic meningoencephalitis caused by Naegleria fowleri in Bangladesh
Sign Up to like & getrecommendations! Published in 2019 at "Parasitology Research"
DOI: 10.1007/s00436-019-06463-y
Abstract: We present the first recognized case of primary amebic meningoencephalitis (PAM) caused by Naegleria fowleri in a 15-year-old male from Bangladesh. He performed daily nasal rinsing with untreated ground water and bathed in untreated ground… read more here.
Keywords: primary amebic; case primary; naegleria fowleri; amebic meningoencephalitis ... See more keywords
Naegleria fowleri-associated meningoencephalitis in a cow in Southern Brazil-first molecular detection of N. fowleri in Brazil.
Sign Up to like & getrecommendations! Published in 2021 at "Parasitology research"
DOI: 10.1007/s00436-021-07209-5
Abstract: Naegleria fowleri, a free-living and thermophilic ameba, is the etiological agent of primary amebic meningoencephalitis (PAM). PAM is a rare and highly fatal neurologic disease in humans, and has been rarely documented in animal species.… read more here.
Keywords: fowleri; naegleria fowleri; fowleri associated; associated meningoencephalitis ... See more keywords
The type 2 statins, cerivastatin, rosuvastatin and pitavastatin eliminate Naegleria fowleri at low concentrations and by induction of programmed cell death (PCD).
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104784
Abstract: Primary Amoebic Encephalitis due to Naegleria fowleri species is a fatal infection of the Central Nervous System mostly affecting children and young adults. Infections often occur after performance of risk activities in aquatic habitats such… read more here.
Keywords: rosuvastatin pitavastatin; naegleria fowleri; programmed cell; type statins ... See more keywords
HMG-CoA Reductase Inhibitors as Drug Leads against Naegleria fowleri.
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DOI: 10.1021/acschemneuro.0c00428
Abstract: Primary amebic meningoencephalitis (PAM), caused by the free-living ameba Naegleria fowleri, has a fatality rate of over 97%. Treatment of PAM relies on amphotericin B in combination with other drugs, but few patients have survived… read more here.
Keywords: hmg coa; fowleri; naegleria fowleri; drug ... See more keywords
Investigating the interactive effects of temperature, pH, and salinity on Naegleria fowleri persistence
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Eukaryotic Microbiology"
DOI: 10.1111/jeu.12964
Abstract: Naegleria fowleri causes primary amoebic meningoencephalitis, a deadly infection that occurs when free‐living amoebae enter the nose via freshwater and travel to the brain. N. fowleri naturally thrives in freshwater and soil and is thought… read more here.
Keywords: persistence; naegleria fowleri; effects temperature; temperature salinity ... See more keywords
Naegleria fowleri immunization modifies lymphocytes and APC of nasal mucosa
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DOI: 10.1111/pim.12508
Abstract: We investigated whether intranasal immunization with amoebic lysates plus cholera toxin modified the populations of T and B lymphocytes, macrophages and dendritic cells by flow cytometry from nose‐associated lymphoid tissue (NALT), cervical lymph nodes (CN),… read more here.
Keywords: immunization; immunized mice; naegleria fowleri; fowleri immunization ... See more keywords
Identification of differential protein recognition pattern between Naegleria fowleri and Naegleria lovaniensis
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DOI: 10.1111/pim.12715
Abstract: Many pathogenicity factors are involved in the development of primary amoebic meningoencephalitis (PAM) caused by N fowleri. However, most of them are not exclusive for N fowleri and they have not even been described in… read more here.
Keywords: protein; fowleri naegleria; naegleria fowleri; recognition ... See more keywords
A 250 kDa Glycoprotein of Naegleria fowleri Induces Protection and Modifies the Expression of α4β1 and LFA-1 on T and B Lymphocytes in Mouse Meningitis Model.
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DOI: 10.1111/pim.12882
Abstract: AIMS the aims of this work were to evaluate the protective role of 250 kDa polypeptide band of Naegleria fowleri. METHODS AND RESULTS We designed an immunization strategi in Balb/c mice which were inoculated by i.n.… read more here.
Keywords: protection; kda; 250 kda; naegleria fowleri ... See more keywords
Adaptive iron utilization compensates for the lack of an inducible uptake system in Naegleria fowleri and represents a potential target for therapeutic intervention
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007759
Abstract: Naegleria fowleri is a single-cell organism living in warm freshwater that can become a deadly human pathogen known as a brain-eating amoeba. The condition caused by N. fowleri, primary amoebic meningoencephalitis, is usually a fatal… read more here.
Keywords: potential target; target therapeutic; naegleria fowleri; therapeutic intervention ... See more keywords
Naegleria fowleri from Pakistan Has Type-2 Genotype
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DOI: 10.18502/ijpa.v17i1.9015
Abstract: Background: Primary amoebic meningoencephalitis (PAM) is an acute and fulminant CNS infection caused by Naegleria fowleri. Recreational activities and ritual ablution with contaminated warm fresh water are the main reason of PAM. Pakistan ranked the… read more here.
Keywords: fowleri; naegleria fowleri; water; genotype ... See more keywords
Development of a dose-response model for Naegleria fowleri.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of water and health"
DOI: 10.2166/wh.2018.181
Abstract: This study develops novel dose-response models for Naegleria fowleri from selected peer-reviewed experiments on the virulence based on the intranasal exposure pathway. One data set measured the response of mice intranasally inoculated with the amebae… read more here.
Keywords: dose response; risk; response; naegleria fowleri ... See more keywords