Neue arzneitherapeutische Optionen bei nichtalkoholischer Fettlebererkrankung
Sign Up to like & getrecommendations! Published in 2020 at "Der Internist"
DOI: 10.1007/s00108-020-00801-4
Abstract: Die nichtalkoholische Fettlebererkrankung („nonalcoholic fatty liver disease“ [NAFLD]) breitet sich weltweit weiter aus, betrifft mittlerweile 25 % der Erwachsenen und geht mit einer erhöhten Gesamt- und leberspezifischen Mortalität einher. Die NAFLD verläuft chronisch und ist Folge… read more here.
Keywords: bei; arzneitherapeutische optionen; disease; nafld ... See more keywords
Lean non-alcoholic fatty liver disease (lean NAFLD): characteristics, metabolic outcomes and risk factors from a 7-year prospective, community cohort study from Sri Lanka
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology International"
DOI: 10.1007/s12072-018-9916-4
Abstract: IntroductionWhile patients with non-alcoholic fatty liver disease (NAFLD) are mostly overweight or obese, some are lean.MethodsIn a community-based follow-up study (baseline and follow-up surveys performed in 2007 and 2014), we investigated and compared the clinical… read more here.
Keywords: lean nafld; non lean; risk factors; nafld ... See more keywords
Effect of melatonin therapy on the non-alcoholic steatohepatitis patients: a systematic review and meta-analysis on clinical trial studies.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174154
Abstract: Melatonin has shown promising effects in controlling the progress of non-alcoholic fatty liver disease (NAFLD) introducing it as a possible candidate for NAFLD treatment. In this context, the current study is aimed to evaluate melatonin's… read more here.
Keywords: non alcoholic; treatment; nafld; effect melatonin ... See more keywords
Disease-specific eQTL screening reveals an anti-fibrotic effect of AGXT2 in non-alcoholic fatty liver disease.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2021.04.011
Abstract: BACKGROUND & AIMS Nonalcoholic fatty liver disease (NAFLD) poses an impending clinical burden. Genome-wide association studies have revealed a limited contribution of genomic variants to the disease, requiring alternative but robust approaches to identify disease-associated… read more here.
Keywords: disease specific; agxt2; fatty liver; disease ... See more keywords
Alternative treatment methods attenuate the development of NAFLD: A review of resveratrol molecular mechanisms and clinical trials.
Sign Up to like & getrecommendations! Published in 2017 at "Nutrition"
DOI: 10.1016/j.nut.2016.09.001
Abstract: Nonalcoholic fatty liver disease (NAFLD) is considered to be one of the most common liver pathologies that occur widely among societies with a predominance of the Western dietary pattern. NAFLD may progress from hepatic steatosis… read more here.
Keywords: treatment methods; treatment; nafld; clinical trials ... See more keywords
Heat-Processed Diet Rich in Advanced Glycation End Products Induced the Onset and Progression of NAFLD via Disrupting Gut Homeostasis and Hepatic Lipid Metabolism.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c08360
Abstract: Epidemiologic studies have suggested an association between the consumption of dietary advanced glycation end products (dAGEs) and the incidence of nonalcoholic fatty liver disease (NAFLD). However, the precise mechanism by which dAGEs induce NAFLD development,… read more here.
Keywords: gut homeostasis; advanced glycation; end products; glycation end ... See more keywords
Hepatic Steatosis—a complex interaction of germs, genes and grub.
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Research"
DOI: 10.1038/s41390-018-0143-4
Abstract: Non-alcoholic fatty liver disease (NAFLD) has a prevalence of 7–10% among children in the developed world, making it the most common cause of chronic liver disease in this population. Its prevalence is rising concomitant with… read more here.
Keywords: hepatic steatosis; disease; nafld; study ... See more keywords
Oxidative stress and cardiometabolic biomarkers in patients with non-alcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-97686-6
Abstract: Oxidative stress is assumed to be the underlying feature of non-alcoholic fatty liver disease (NAFLD). To our knowledge, the mutual involvement of redox status homeostasis parameters [i.e., advanced oxidation protein products (AOPP), pro-oxidant-antioxidant balance (PAB),… read more here.
Keywords: status; stress cardiometabolic; related factor; nafld ... See more keywords
Life’s Crucial 9 and NAFLD from association to SHAP-interpreted machine learning predictions
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-92777-0
Abstract: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease worldwide. Cardiovascular disease (CVD) and NAFLD share multiple common risk factors. Life’s Crucial 9 (LC9), a novel indicator for comprehensive assessment of cardiovascular… read more here.
Keywords: cause mortality; machine; nafld; life crucial ... See more keywords
NAFLD 2020: The State of the Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Gastroenterology"
DOI: 10.1053/j.gastro.2020.01.052
Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease with a worldwide prevalence of 25%. In the US, NAFLD and its subtype, nonalcoholic steatohepatitis (NASH), affect 30% and 5% of the population, respectively.… read more here.
Keywords: nafld 2020; disease; nafld; disease nafld ... See more keywords
HCC Surveillance in NAFLD patients.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in liver disease"
DOI: 10.1055/a-1957-8540
Abstract: The burden for hepatocellular carcinoma (HCC) attributed to nonalcoholic fatty liver disease (NAFLD) continues to grow in parallel with rising global trends in obesity. The risk of HCC is elevated among patients with NAFLD-related cirrhosis… read more here.
Keywords: hcc surveillance; surveillance; nafld; risk ... See more keywords