Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease
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DOI: 10.1002/cam4.1078
Abstract: In an increasing proportion of cases, hepatocellular carcinoma (HCC) develops in patients with nonalcoholic fatty liver disease (NAFLD). Mutations in telomerase reverse transcriptase (hTERT) are associated with familial liver diseases. The aim of this study… read more here.
Keywords: liver disease; htert; nafld hcc; liver ... See more keywords
Tumor suppressor ZHX2 inhibits NAFLD–HCC progression via blocking LPL-mediated lipid uptake
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DOI: 10.1038/s41418-019-0453-z
Abstract: Non-alcoholic fatty liver disease (NAFLD) leads to hepatocellular carcinoma (HCC). However, the underlying mechanism remains largely unclear. Here, we investigated the role of the tumor suppressor Zinc fingers and homeoboxes 2 (ZHX2) in the progression… read more here.
Keywords: hcc; lpl; zhx2; progression ... See more keywords
Abstract A18: microRNA-206 as a potential therapeutic approach for highly-associated NAFLD and HCC
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.transcontrol16-a18
Abstract: Background and Significance: Non-alcoholic fatty liver disease (NAFLD) is a major risk factor for the development of hepatocellular carcinoma (HCC). Even with successful surgical removal, the presence of NAFLD is associated with an increased recurrence… read more here.
Keywords: highly associated; hcc mice; hcc; mir 206 ... See more keywords
Is Hepatocellular Carcinoma in Fatty Liver Different to Non-Fatty Liver?
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DOI: 10.3390/nu14183875
Abstract: Background: Non-alcoholic fatty liver disease (NAFLD) has become the most prevalent liver disease in Australia and is recognised to play a role in the development of hepatocellular carcinoma (HCC). There are no clear guidelines regarding… read more here.
Keywords: hepatocellular carcinoma; non nafld; fatty liver; hcc ... See more keywords
Fatty liver disease, an emerging etiology of hepatocellular carcinoma in Argentina
Sign Up to like & getrecommendations! Published in 2018 at "World Journal of Hepatology"
DOI: 10.4254/wjh.v10.i1.41
Abstract: AIM To investigate any changing trends in the etiologies of hepatocellular carcinoma (HCC) in Argentina during the last years. METHODS A longitudinal cohort study was conducted by 14 regional hospitals starting in 2009 through 2016.… read more here.
Keywords: hcc; fatty liver; etiology; liver disease ... See more keywords