Letter to the Editor: Saroglitazar for treatment of NAFLD and NASH.
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32094
Abstract: Despite being one of the common diseases, the treatment options for nonalcoholic steatohepatitis (NASH) are still limited. Recently, Gawrieh et al. demonstrated significant improvement in liver enzymes and liver fat content (LFC) in nonalcoholic fatty… read more here.
Keywords: saroglitazar treatment; treatment; editor saroglitazar; nafld nash ... See more keywords
Preparing for the NASH epidemic: A call to action
Sign Up to like & getrecommendations! Published in 2021 at "Obesity"
DOI: 10.1002/oby.23250
Abstract: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are common conditions with a rising burden. Yet there are significant management gaps between clinical guidelines and practice in patients with NAFLD and NASH. Further, there… read more here.
Keywords: call action; nash epidemic; epidemic call; preparing nash ... See more keywords
Applying Non-Invasive Fibrosis Measurements in NAFLD/NASH: Progress to Date
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Medicine"
DOI: 10.1007/s40290-019-00305-z
Abstract: Nonalcoholic fatty liver disease (NAFLD) has now become a worldwide health issue due to the obesity epidemic, affecting approximately 90% of the obese population and 15–40% of the general population. It is the most common… read more here.
Keywords: fibrosis stage; fibrosis; invasive fibrosis; non invasive ... See more keywords
The role of IFN in the development of NAFLD and NASH.
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.08.013
Abstract: Non-alcoholic fatty liver disease (NAFLD) and its progressive inflammatory form non-alcoholic steatohepatitis (NASH) are major health challenges due to a significant increase in their incidence and prevalence. While NAFLD is largely benign, the chronic liver… read more here.
Keywords: ifn development; nafld nash; progression; development ... See more keywords
Pyroptosis: An inflammatory link between NAFLD and NASH with potential therapeutic implications.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2018.01.017
Abstract: Department of Pharmacology and Toxicology, Hepatobiology and Toxicology Program, University of Louisville Alcohol Research Center, University of Louisville Health Sciences Center, Louisville, KY 40292, USA; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute… read more here.
Keywords: university; inflammatory link; link nafld; nafld nash ... See more keywords
Effects of newer antidiabetic drugs on nonalcoholic fatty liver and steatohepatitis: think out of the box!
Sign Up to like & getrecommendations! Published in 2019 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2019.154001
Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western societies and a major cause of hepatic disease worldwide. Its more severe type, namely nonalcoholic steatohepatitis (NASH), may result in the… read more here.
Keywords: antidiabetic drugs; fatty liver; effects newer; disease ... See more keywords
Non-alcoholic fatty liver disease and steatohepatitis: State of the art on effective therapeutics based on the gold standard method for diagnosis
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2020.101049
Abstract: Objective The prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NAFLD/NASH) is increasing. NAFLD/NASH may progress to cirrhosis and hepatocellular carcinoma. However, most patients with NAFLD/NASH will die from a vascular cause. There are… read more here.
Keywords: alcoholic fatty; fatty liver; non alcoholic; nafld nash ... See more keywords
Epigenetics in NAFLD/NASH: Targets and Therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological research"
DOI: 10.1016/j.phrs.2021.105484
Abstract: Recently non-alcoholic fatty liver disease (NAFLD) has grabbed considerable scientific attention, owing to its rapid increase in prevalence worldwide and growing burden on end-stage liver diseases. Metabolic syndrome including obesity, diabetes, and hypertension poses a… read more here.
Keywords: nash targets; etiology; disease; nafld nash ... See more keywords
Prevalence and stratification of NAFLD/NASH in a UK and US cohort using non-invasive multiparametric MRI
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hepatology"
DOI: 10.1016/s0168-8278(18)31359-x
Abstract: There is a clear need to assess the prevalence of NAFLD and NASH in the general population. MRI iron corrected T1 (cT1) and has been shown to correlate with liver inflammation and fibrosis, and liver-related… read more here.
Keywords: prevalence stratification; stratification nafld; prevalence; nafld nash ... See more keywords
Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-022-28138-6
Abstract: Nonalcoholic fatty liver disease (NAFLD) is an important health concern worldwide and progresses into nonalcoholic steatohepatitis (NASH). Although prevalence and severity of NAFLD/NASH are higher in men than premenopausal women, it remains unclear how sex… read more here.
Keywords: formyl peptide; liver disease; fatty liver; sex ... See more keywords
Real-world Comorbidity Burden, Health Care Utilization, and Costs of Nonalcoholic Steatohepatitis Patients With Advanced Liver Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000001409
Abstract: Supplemental Digital Content is available in the text. Goals: This study evaluates the real-world comorbidity burden, health care resource utilization (HRU), and costs among nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH) patients with advanced liver diseases… read more here.
Keywords: comorbidity burden; liver diseases; advanced liver; nafld nash ... See more keywords