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NAG-1/GDF15 protects against streptozotocin-induced type 1 diabetes by inhibiting apoptosis, preserving beta-cell function, and suppressing inflammation in pancreatic islets

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Published in 2022 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2022.111643

Abstract: The loss of functional insulin-producing β-cells is a hallmark of type 1 diabetes mellitus (T1DM). Previously, we reported that the non-steroidal anti-inflammatory drug activated gene-1, or growth differentiation factor-15 (NAG-1/GDF15) inhibits obesity and improves insulin… read more here.

Keywords: gdf15; stz; type diabetes; nag gdf15 ... See more keywords