Articles with "naive cells" as a keyword



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Improving naive B cell isolation by absence of CD45RB glycosylation and CD27 expression in combination with BCR isotype

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Published in 2022 at "European Journal of Immunology"

DOI: 10.1002/eji.202250013

Abstract: In past years ex vivo and in vivo experimental approaches involving human naive B cells have proven fundamental for elucidation of mechanisms promoting B cell differentiation in both health and disease. For such studies, it… read more here.

Keywords: cell; naive cell; cell isolation; naive cells ... See more keywords
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Naive B Cells with High‐Avidity Germline‐Encoded Antigen Receptors Produce Persistent IgM+ and Transient IgG+ Memory B Cells

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Published in 2018 at "Immunity"

DOI: 10.1016/j.immuni.2018.04.019

Abstract: &NA; Although immune memory often lasts for life, this is not the case for certain vaccines in some individuals. We sought a mechanism for this phenomenon by studying B cell responses to phycoerythrin (PE). PE… read more here.

Keywords: germline encoded; memory cells; antigen; naive cells ... See more keywords
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Lymphopenia-induced lymphoproliferation drives activation of naive T cells and expansion of regulatory populations

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Published in 2021 at "iScience"

DOI: 10.1016/j.isci.2021.102164

Abstract: Summary Chemotherapy pre-conditioning is an essential component of chimeric antigen receptor transduced cell therapy. Acute lymphopenia-induced proliferation (LIP) is known to be driven primarily by homeostatic cytokines, but little is known on the underlying mechanisms… read more here.

Keywords: expansion; lymphoproliferation drives; induced lymphoproliferation; lymphopenia induced ... See more keywords
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Naive T cells can be primed for tissue residency

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Published in 2019 at "Nature Reviews Immunology"

DOI: 10.1038/s41577-019-0239-z

Abstract: This study sheds light onto the processes by which naive T cells are preconditioned for tissue residency. read more here.

Keywords: tissue residency; naive cells; primed tissue; cells primed ... See more keywords
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Naive infection predicts reservoir diversity and is a formidable hurdle to HIV eradication

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Published in 2021 at "JCI Insight"

DOI: 10.1172/jci.insight.150794

Abstract: Historically, naive cells have been considered inconsequential to HIV persistence. Here, we compared the contributions of naive and memory cells to the reservoirs of individuals with a spectrum of reservoir sizes and variable immunological control.… read more here.

Keywords: naive infection; hiv; infection; reservoir diversity ... See more keywords
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Distinct In Vitro T-Helper 17 Differentiation Capacity of Peripheral Naive T Cells in Rheumatoid and Psoriatic Arthritis

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Published in 2018 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2018.00606

Abstract: Background The T-helper 17 (Th17) cells have a prominent role in inflammation as well as in bone and join destruction in both rheumatoid and psoriatic arthritis (RA and PsA). Here, we studied Th17 cell differentiation in… read more here.

Keywords: psoriatic arthritis; rheumatoid psoriatic; psa patients; differentiation ... See more keywords
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Naive T Cells in Graft Versus Host Disease and Graft Versus Leukemia: Innocent or Guilty?

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.893545

Abstract: The outcome of allogeneic hematopoietic cell transplantation (allo-HCT) largely depends on the development and management of graft-versus-host disease (GvHD), infections, and the occurrence of relapse of malignancies. Recent studies showed a lower incidence of chronic… read more here.

Keywords: graft versus; cell; gvhd; naive cells ... See more keywords
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Machine learning and BP neural network revealed abnormal B cell infiltration predicts the survival of lung cancer patients

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.882018

Abstract: FAM83A gene is related to the invasion and metastasis of various tumors. However, the abnormal immune cell infiltration associated with the gene is poorly understood in the pathogenesis and prognosis of NSCLC. Based on the… read more here.

Keywords: infiltration; neural network; cell infiltration; machine learning ... See more keywords