Network Features and Dynamical Landscape of Naive and Primed Pluripotency.
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DOI: 10.1016/j.bpj.2017.10.033
Abstract: Although the broad and unique differentiation potential of pluripotent stem cells relies on a complex transcriptional network centered around Oct4, Sox2, and Nanog, two well-distinct pluripotent states, called "naive" and "primed", have been described in vitro… read more here.
Keywords: network; naive primed; pluripotency; network features ... See more keywords
Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution
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DOI: 10.1016/j.celrep.2018.12.099
Abstract: Summary Conventional human embryonic stem cells are considered to be primed pluripotent but can be induced to enter a naive state. However, the transcriptional features associated with naive and primed pluripotency are still not fully… read more here.
Keywords: single cell; cell; pluripotent; naive primed ... See more keywords
Cell-Surface Proteomics Identifies Differences in Signaling and Adhesion Protein Expression between Naive and Primed Human Pluripotent Stem Cells
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DOI: 10.1016/j.stemcr.2020.03.017
Abstract: Summary Naive and primed human pluripotent stem cells (hPSC) provide valuable models to study cellular and molecular developmental processes. The lack of detailed information about cell-surface protein expression in these two pluripotent cell types prevents… read more here.
Keywords: protein expression; human pluripotent; naive primed; cell surface ... See more keywords