Nalfurafine modulates the reinforcing effects of oxycodone in male and female adolescent C57BL/6J mice
Sign Up to like & getrecommendations! Published in 2020 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2020.108244
Abstract: Addiction to prescription opioid, such as oxycodone, has affected millions of adolescents and young adults. Kappa opioid receptor (KOP-r) agonist can counterbalance the euphoria effects of mu opioid agonists like oxycodone. Nalfurafine is a KOP-r… read more here.
Keywords: nalfurafine; male female; mice; female adolescent ... See more keywords
Randomized controlled trial of nalfurafine for refractory pruritus in hemodialysis patients
Sign Up to like & getrecommendations! Published in 2023 at "Renal Failure"
DOI: 10.1080/0886022x.2023.2175590
Abstract: Abstract Background: Chronic kidney disease-associated pruritus (CKD-aP) is very common and sometimes refractory to treatment in hemodialysis patients. In a trial conducted in Japan, nalfurafine, effectively reduced itching of treatment-resistant CKD-aP. Our present bridging study… read more here.
Keywords: trial; ckd; refractory pruritus; hemodialysis patients ... See more keywords