Silencing the PIK3CA Gene Enhances the Sensitivity of Childhood Leukemia Cells to Chemotherapy Drugs by Suppressing the Phosphorylation of Akt
Sign Up to like & getrecommendations! Published in 2019 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2019.60.2.182
Abstract: Purpose This study aimed to investigate the effects of PIK3CA on the sensitivity of acute B lymphocytic leukemia cells (Nalm-6 cells) to chemotherapy drugs. Materials and Methods Children's normal B lymphocytes and Nalm-6 cells were… read more here.
Keywords: chemotherapy drugs; leukemia cells; group; sensitivity ... See more keywords
Exosomes derived from bone marrow stromal cells decrease the sensitivity of leukemic cells to etoposide.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology letters"
DOI: 10.3892/ol.2017.6509
Abstract: The aim of the study was to investigate the effect of exosomes derived from bone marrow stromal cells (BM-SCs) on the chemoresistant characteristics of nalm-6 cells treated with etoposide (VP16). The present study isolated exosomes… read more here.
Keywords: derived bone; marrow stromal; stromal cells; exosomes derived ... See more keywords