Awakening Allies for Breaking Microenvironment Barriers: NIR-II Guided Orthogonal Activation of Tumor-infiltrating Mast Cells for Efficient Nano-drug Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300420
Abstract: Mast cells (MCs), powerful immune cells that heavily infiltrate cancer cells, play a crucial role in tumor formation. Activated MCs can release histamine and a family of proteases through degranulation effects, concurrently achieving endothelial junction… read more here.
Keywords: tumor infiltrating; activation tumor; mast cells; tumor ... See more keywords
Streamlined plug-in aerosol prototype for reconfigurable manufacture of nano-drug delivery systems.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2022.121511
Abstract: The significant advances in nano-drug delivery systems (NDDS) for anticancer agents have led to the development of computational techniques, such as machine learning and neural networks to identify the optimal architectural and compositional design in… read more here.
Keywords: drug; nano drug; drug delivery; dox fachi ... See more keywords
Potential Therapies and Diagnosis Based on Golgi-targeted Nano Drug Delivery Systems.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological research"
DOI: 10.1016/j.phrs.2021.105861
Abstract: With the rapid development of nanotechnology, organelle-targeted nano drug delivery systems (NDDSs) have emerged as a potential method which can transport drugs specifically to the subcellular compartments like nucleus, mitochondrion, lysosome, endoplasmic reticulum (ER) and… read more here.
Keywords: targeted nano; golgi targeted; drug delivery; golgi ... See more keywords
Glutathione and Esterase Dual-Responsive Smart Nano-drug Delivery System Capable of Breaking the Redox Balance for Enhanced Tumor Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c01155
Abstract: Conventional chemotherapy usually fails to achieve its intended effect because of the poor water solubility, poor tumor selectivity, and low tumor accumulation of chemotherapy drugs. The systemic toxicity of chemotherapy agents is also a problem… read more here.
Keywords: tumor; drug delivery; drug; smart nano ... See more keywords
Selection of an aggregation-caused quenching-based fluorescent tracer for imaging studies in nano drug delivery systems.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d3nr01018j
Abstract: In order to develop and optimize nano drug delivery systems (NDDSs), it is crucial to understand their in vivo fate. We previously found that P2 (Aza-BODIPY) and P4 (BODIPY) as aggregation-caused quenching (ACQ) probes could… read more here.
Keywords: delivery systems; caused quenching; aggregation caused; aza bodipy ... See more keywords
Folic acid–maltodextrin polymer coated magnetic graphene oxide as a NIR-responsive nano-drug delivery system for chemo-photothermal synergistic inhibition of tumor cells
Sign Up to like & getrecommendations! Published in 2023 at "RSC Advances"
DOI: 10.1039/d3ra02306k
Abstract: The combination of chemo-photothermal therapy with high efficiency and fewer side effects has a good application prospect in cancer treatment. It is of great significance to construct a nano-drug delivery system with cancer cell targeting,… read more here.
Keywords: chemo photothermal; drug delivery; drug; tumor ... See more keywords
Study on Nano Drug Particles in the Diagnosis and Treatment of Alzheimer's Disease in the Elderly
Sign Up to like & getrecommendations! Published in 2022 at "Bioinorganic Chemistry and Applications"
DOI: 10.1155/2022/3335581
Abstract: Objective To study the clinical effect of nano drug particles in the diagnosis and treatment of Alzheimer's disease in the elderly, we promote the research on the treatment of Alzheimer's disease and provide basis. Methods… read more here.
Keywords: drug particles; alzheimer disease; group; treatment ... See more keywords
Construction of a New Dual-Responsive Nano-Drug Delivery System for Matrix Metalloproteinases and Adenosine Triphosphate in Ovarian Cancer Using Nanomicelles.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2022.3303
Abstract: In this manuscript we constructed a dual-responsive nano-drug delivery system for matrix metalloproteinases and ATP in ovarian cancer microenvironment. The nanomicelle PCL-DNA/DOX-Peptide-PEG was prepared by intercalating doxorubicin hydrochloride between C and G base pairs of… read more here.
Keywords: responsive nano; delivery system; drug delivery; dual responsive ... See more keywords
Magnetic Resonance Imaging combined with Computed Tomography in the Diagnosis of Multiple Myeloma and the Killing Effect of Doxorubicin Nano-drug Delivery System on Myeloma Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.3.41
Abstract: It was to adopt magnetic resonance imaging (MRI) combined with computed tomography (CT) to diagnose multiple myeloma (MM) and evaluate the therapeutic effect of the doxorubicin nano-drug delivery system on MM, providing a more effective… read more here.
Keywords: myeloma; group; drug delivery; doxorubicin nano ... See more keywords
Analysis of the Effect of a New Type of Nano-drug Carrier Preparation on the Pathological Changes in Lung and Inducible Nitric-Oxide Synthase Expression in Severe Sepsis.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.8.1
Abstract: To explore the effect of a new type of nano-drug carrier preparation on the pathological changes in severe sepsis lung and inducible nitric oxide synthase (iNOS) expression, a new type of nano-drug carrier preparation was… read more here.
Keywords: drug carrier; carrier preparation; drug; nano drug ... See more keywords
Recent Advances in Nano-Drug Delivery Systems for the Treatment of Diabetic Wound Healing
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s395438
Abstract: Abstract Diabetes mellitus (DM) induced wound healing impairment remains a serious health problem and burden on the clinical obligation for high amputation rates. Based on the features of wound microenvironment, biomaterials loading specific drugs can… read more here.
Keywords: wound; delivery systems; drug delivery; nano drug ... See more keywords