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Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.01.010
Abstract: In this study we have investigated the effects of combination treatment involving ERL (Erlotinib) with a glycyrrhetinic acid analog, CDODA-Me in overcoming ERL resistance, and to improve the oral bioavailability of this treatment using self-Nano-emulsifying…
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Keywords:
combination;
emulsifying drug;
drug;
self nano ... See more keywords
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Published in 2021 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2021.1973495
Abstract: Abstract Prasugrel Hydrochloride (PHCl) is an antiplatelet drug. It is a class II drug with variable bioavailability. The objective of this work was to enhance the solubility and hence the bioavailability and efficacy of PHCl.…
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Keywords:
prasugrel;
bioavailability;
drug;
self nano ... See more keywords
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Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548312.49404.54
Abstract: Objectives: Poor water solubility is one of the reasons for erratic absorption after oral administration of furosemide (FSM), an antihypertensive loop diuretic. Self nano emulsifying drug delivery system (SNEDDS) is a novel drug delivery system…
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Keywords:
drug delivery;
emulsifying drug;
drug;
self nano ... See more keywords
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Published in 2020 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-020-01644-w
Abstract: Pentoxifylline (PTX), an anti-hemorrhage drug used in the treatment of intermittent claudication, is extensively metabolized by the liver resulting in a reduction of the therapeutic levels within a short duration of time. Self-nano-emulsifying drug delivery…
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Keywords:
drug delivery;
emulsifying drug;
drug;
self nano ... See more keywords
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Published in 2022 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2022v14i3.44178
Abstract: The most fundamental important extensive constitutive of drug molecules to be available for systemic absorption is aqueous solubility; subsequently, that is the nature of GIT fluid. When the drug molecules become solubilized, it has to…
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Keywords:
self nano;
bioavailability;
nano emulsifying;
drug delivery ... See more keywords
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Published in 2020 at "Indian Journal of Pharmaceutical Sciences"
DOI: 10.36468/pharmaceutical-sciences.648
Abstract: In the present study artemether and lumefantrine self-nano emulsifying drug delivery system formulations were prepared using combination of these drugs with Capmul medical countermeasure, oleic acid and Tween 80. The particle size and zeta potential…
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Keywords:
delivery system;
drug delivery;
emulsifying drug;
self nano ... See more keywords