A DNA Nano Firework for Imaging and Inhibitor Screening of Flap Endonuclease 1 in Living Cells.
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DOI: 10.1021/acs.analchem.3c00930
Abstract: In situ observation of changes in the activity of marker proteins in living cells is crucial for both biomarker-based disease diagnosis and drug screening. Flap endonuclease 1 (FEN1) has been recognized as a broad-spectrum cancer… read more here.
Keywords: nano firework; living cells; flap endonuclease; activity ... See more keywords