Nano-hydroxyapatite improves intestinal absorption of acetazolamide (BCS Class IV drug)–but how?
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DOI: 10.1371/journal.pone.0268067
Abstract: We earlier reported that coating poorly water-soluble drugs with nano-hydroxyapatite (nano-HAP) improves bioavailability after oral administration. In the present study, we coated BCS Class IV drug acetazolamide (AZ) with nano-HAP (AZ/HAP formulation), and investigated its… read more here.
Keywords: nano hydroxyapatite; bcs class; nano hap; permeability ... See more keywords