Near-infrared-traceable DNA nano-hydrolase: specific eradication of telomeric G-overhang in vivo
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DOI: 10.1093/nar/gkaa693
Abstract: Abstract Telomeric DNA, whose length homeostasis is closely correlated with immortality of cancer cells, is regarded as a molecular clock for cellular lifespan. Regarding the capacity in forming G-quadruplex, G-rich 3′-overhang (G-overhang) has been considered… read more here.
Keywords: nano hydrolase; overhang; telomeric overhang; dna nano ... See more keywords