Esterase-Activated, pH-Responsive, and Genetically Targetable Nano-Prodrug for Cancer Cell Photo-Ablation.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202207535
Abstract: Activatable prodrugs have drawn considerable attention for cancer cell ablation owing to their high specificity in drug delivery systems. However, phototheranostic prodrugs with dual organelle-targeting and synergistic effects are still rare due to low intelligence… read more here.
Keywords: nano prodrug; ablation; genetically targetable; esterase activated ... See more keywords
Carrier‐free Janus nano‐prodrug based on camptothecin and gemcitabine: Reduction‐triggered drug release and synergistic in vitro antiproliferative effect in multiple cancer cells
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DOI: 10.1016/j.ijpharm.2018.08.041
Abstract: Graphical abstract Schematic diagram of the self‐delivery of Janus nano‐prodrug CPT‐SS‐GEM nanoparticles. Figure. No Caption available. Abstract A carrier‐free and reduction‐degradable Janus prodrug, termed as CPT‐SS‐GEM, was fabricated by redox‐sensitive disulfide bond linked gemcitabine and… read more here.
Keywords: nano prodrug; cpt gem; prodrug; janus nano ... See more keywords