What if the number of nanotoxicity data is too small for developing predictive Nano-QSAR models? An alternative read-across based approach for filling data gaps.
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DOI: 10.1039/c7nr02211e
Abstract: Over the past decade, computational nanotoxicology, in particular Quantitative Structure-Activity Relationship models (Nano-QSAR) that help in assessing the biological effects of nanomaterials, have received much attention. In effect, a solid basis for uncovering the relationships… read more here.
Keywords: data small; number nanotoxicity; nano qsar; nanotoxicity data ... See more keywords
Modeling of Interactions between the Zebrafish Hatching Enzyme ZHE1 and A Series of Metal Oxide Nanoparticles: Nano-QSAR and Causal Analysis of Inactivation Mechanisms
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DOI: 10.3390/nano7100330
Abstract: The quantitative relationships between the activity of zebrafish ZHE1 enzyme and a series of experimental and physicochemical features of 24 metal oxide nanoparticles were revealed. Vital characteristics of the nanoparticles’ structure were reflected using both… read more here.
Keywords: nano qsar; oxide nanoparticles; metal oxide; inactivation ... See more keywords