Remodeling Tumor-Associated Neutrophils to Enhance Dendritic Cell-Based HCC Neoantigen Nano-Vaccine Efficiency.
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DOI: 10.1002/advs.202105631
Abstract: Hepatocellular carcinoma (HCC) commonly emerges in an immunologically "cold" state, thereafter protects it away from cytolytic attack by tumor-infiltrating lymphocytes, resulting in poor response to immunotherapy. Herein, an acidic/photo-sensitive dendritic cell (DCs)-based neoantigen nano-vaccine has… read more here.
Keywords: tumor; hcc; nano vaccine; tumor associated ... See more keywords
Immunization against Pseudomonas aeruginosa using Alg-PLGA nano-vaccine
Sign Up to like & getrecommendations! Published in 2021 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2021.52217.11813
Abstract: Objective(s): Pseudomonas aeruginosa is the bacterium that causes of pulmonary infection among chronically hospitalized patients. Alginate is a common surface antigen of P. aeruginosa with a constant structure that which makes it an appropriate target… read more here.
Keywords: pseudomonas aeruginosa; alginate plga; vaccine; nano vaccine ... See more keywords
Fast antibody responses by immuno-targeting and nanotechnology strategies versus HBsAg vaccine
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DOI: 10.22038/ijbms.2021.52715.11896
Abstract: Objective(s): Though immunization with HBsAg has been routine since the 1980s, it has numerous limitations such as low or none humoral immune responses. Today, nanotechnology is used in vaccinology to achieve higher potency. The present… read more here.
Keywords: hbsag; fast antibody; humoral immune; nano vaccine ... See more keywords
Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine
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DOI: 10.3389/fimmu.2019.01015
Abstract: Personalized cancer vaccines hold promises for future cancer therapy. Targeting neoantigens is perceived as more beneficial compared to germline, non-mutated antigens. However, it is a practical challenge to identify and vaccinate patients with neoantigens. Here… read more here.
Keywords: cancer nano; germline epitopes; cancer; vaccine ... See more keywords
Case Report: Pathological Complete Response in a Lung Metastasis of Phyllodes Tumor Patient Following Treatment Containing Peptide Neoantigen Nano-Vaccine
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DOI: 10.3389/fonc.2022.800484
Abstract: Some of the mutant peptides produced by gene mutation transcription and translation have the ability to induce specific T cells, which are called new antigens. Neoantigen-based peptide, DNA, RNA, and dendritic cell vaccines have been… read more here.
Keywords: response; neoantigen nano; nano vaccine; lung metastasis ... See more keywords