An Intelligent Nano-vehicle Armed with Multi-functional Navigation for Precise Delivery of Toll-like Receptor 7/8 Agonist and Immunogenic Cell Death Amplifiers to Eliminate Solid Tumors and Trigger Durable Antitumor Immunity.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202102739
Abstract: Cancer immunotherapy is revolutionary in oncology and hematology. However, a low response rate restricts the clinical benefits of this therapy owing to inadequate T lymphocyte infiltration and low delivery efficiency of immunotherapeutic drugs. Herein, an intelligent… read more here.
Keywords: tumor; nano vehicle; delivery; armed multi ... See more keywords
Targeted Theranostic Nano Vehicle Endorsed with Self-Destruction and Immunostimulatory Features to Circumvent Drug Resistance and Wipe-Out Tumor Reinitiating Cancer Stem Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.202003309
Abstract: The downsides of conventional cancer monotherapies are profound and enormously consequential, as drug-resistant cancer cells and cancer stem cells (CSC) are typically not eliminated. Here, a targeted theranostic nano vehicle (TTNV) is designed using manganese-doped… read more here.
Keywords: cancer stem; drug; cancer; stem cells ... See more keywords
The Potential of Nano-Vehicle Mediated Therapy in Vasculitis and Multiple Sclerosis.
Sign Up to like & getrecommendations! Published in 2017 at "Current pharmaceutical design"
DOI: 10.2174/1381612822666161221151900
Abstract: The induction of immune tolerance towards self-antigens presents as a viable future strategy in the treatment of auto-immune diseases, including vasculitis and multiple sclerosis (MS). As specific targets are currently lacking for vasculitis due to… read more here.
Keywords: vasculitis; vasculitis multiple; multiple sclerosis; potential nano ... See more keywords