Nanobodies and chemical cross-links advance the structural and functional analysis of PI3Kα
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DOI: 10.1073/pnas.2210769119
Abstract: Significance PI3Kα is a dimeric lipid kinase consisting of a catalytic subunit p110α and a regulatory subunit p85α. It controls cell proliferation and survival and is an important therapeutic target for cancer. However, the development… read more here.
Keywords: pi3k; cross links; nanobodies chemical; chemical cross ... See more keywords