Development of a NanoBRET-Based Sensitive Screening Method for CXCR4 Ligands.
Sign Up to like & getrecommendations! Published in 2019 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.9b00182
Abstract: A critical part of the development of CXCR4 modulators is to have a simple and sensitive assay system to complement the search by screening and evaluating the binding affinity. Herein, a NanoBRET assay system was… read more here.
Keywords: nanobret assay; assay system; cxcr4 ligands; development ... See more keywords
A Live-Cell NanoBRET Assay to Monitor RNA–Protein Interactions and Their Inhibition by Small Molecules
Sign Up to like & getrecommendations! Published in 2025 at "ACS Central Science"
DOI: 10.1021/acscentsci.5c00705
Abstract: RNA–protein interactions are critical for cellular processes, including translation, pre-mRNA splicing, post-transcriptional modifications, and RNA stability. Their dysregulation is implicated in diseases such as myotonic dystrophy type 1 (DM1) and amyotrophic lateral sclerosis (ALS). To… read more here.
Keywords: cug exp; protein interactions; rna protein; nanobret assay ... See more keywords