Articles with "nanocage" as a keyword



Enhancing Tumor Immunotherapy by Multivalent Anti‐PD‐L1 Nanobody Assembled via Ferritin Nanocage

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Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202308248

Abstract: Increasing immunotherapy response rate and durability can lead to significant improvements in cancer care. To address this challenge, a novel multivalent immune checkpoint therapeutic platform is constructed through site‐specific ligation of anti‐PD‐L1 nanobody (Nb) on… read more here.

Keywords: immunotherapy; multivalent; tumor; anti nanobody ... See more keywords

3D RNA nanocage for encapsulation and shielding of hydrophobic biomolecules to improve the in vivo biodistribution

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Published in 2020 at "Nano Research"

DOI: 10.1007/s12274-020-2996-1

Abstract: Ribonucleic acid (RNA) nanotechnology platforms have the potential of harboring therapeutics for in vivo delivery in disease treatment. However, the nonspecific interaction between the harbored hydrophobic drugs and cells or other components before reaching the… read more here.

Keywords: rna nanocage; microscopy; hydrophobic biomolecules; nanocage ... See more keywords

A DFT, AIM and NBO study of isoniazid drug delivery by MgO nanocage

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Published in 2019 at "Applied Surface Science"

DOI: 10.1016/j.apsusc.2018.11.005

Abstract: Abstract Density functional theory (DFT), quantum theory of atom in molecule (QTAIM), and natural bond orbital (NBO) have been performed for geometry optimization, binding energy, electronic properties, and adsorption of drug isoniazid (INH) on the… read more here.

Keywords: doped mgonc; drug; mgo nanocage; electronic properties ... See more keywords

Rapidly synthesizing interconnected carbon nanocage by microwave toward high-performance aluminum batteries

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Published in 2020 at "Chemical Engineering Journal"

DOI: 10.1016/j.cej.2020.124407

Abstract: Abstract Cathode materials with specific physicochemical properties are key to the excellent electrochemical performance of aluminum batteries. Here, we propose a catalyst-free microwave pulse radiation method to simply and rapidly convert Ketjen black into inter-connected… read more here.

Keywords: performance aluminum; aluminum batteries; nanocage; carbon nanocage ... See more keywords

Exploring Li4N and Li4O superalkalis as efficient dopants for the Al12N12 nanocage to design high performance nonlinear optical materials with high thermodynamic stability

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Published in 2021 at "Polyhedron"

DOI: 10.1016/j.poly.2021.115145

Abstract: Abstract The influence of superalkalis (Li4N and Li4O) doping on the structural, electrical, optical and nonlinear optical properties of the Al12N12 nanocage has been theoretically investigated through density functional theory. The research findings show the… read more here.

Keywords: li4n li4o; optical materials; superalkalis; al12n12 nanocage ... See more keywords

EGFR Ligand Clustering on E2 Bionanoparticles for Targeted Delivery of Chemotherapeutics to Breast Cancer Cells.

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Published in 2022 at "Bioconjugate chemistry"

DOI: 10.1021/acs.bioconjchem.1c00579

Abstract: Naturally occurring protein nanocages are promising drug carriers because of their uniform size and biocompatibility. Engineering efforts have enhanced the delivery properties of nanocages, but cell specificity and high drug loading remain major challenges. Herein,… read more here.

Keywords: breast; cancer cells; drug; breast cancer ... See more keywords

Design of Zn-, Cu-, and Fe-Coordination Complexes Confined in a Self-Assembled Nanocage.

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Published in 2018 at "Inorganic chemistry"

DOI: 10.1021/acs.inorgchem.7b02852

Abstract: The encapsulation of coordination complexes in a tetragonal prismatic nanocage (1·(BArF)8) built from Zn-porphyrin and macrocyclic Pd-clip-based synthons is described. The functional duality of the guest ligand L1 allows for its encapsulation inside the cage… read more here.

Keywords: coordination; complexes confined; nanocage; chemistry ... See more keywords

Designed Two- and Three-Dimensional Protein Nanocage Networks Driven by Hydrophobic Interactions Contributed by Amyloidogenic Motifs.

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Published in 2019 at "Nano letters"

DOI: 10.1021/acs.nanolett.9b01365

Abstract: Precise manipulation of protein self-assembly by noncovalent interactions into programmed networks to mimic naturally occurring nanoarchitectures in living organisms is a challenge due to its structural heterogeneity, flexibility, and complexity. Herein, by taking advantage of… read more here.

Keywords: protein; three dimensional; protein nanocage; nanocage ... See more keywords

Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials

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Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-25199-x

Abstract: Although various artificial protein nanoarchitectures have been constructed, controlling the transformation between different protein assemblies has largely been unexplored. Here, we describe an approach to realize the self-assembly transformation of dimeric building blocks by adjusting… read more here.

Keywords: building blocks; protein interface; nanocage; interface redesign ... See more keywords

Gram-scale synthesis of a covalent nanocage that preserves the redox properties of encapsulated fullerenes

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Published in 2022 at "Chemical Science"

DOI: 10.1039/d2sc00445c

Abstract: Discrete nanocages provide a way to solubilize, separate, and tune the properties of fullerenes, but these 3D receptors cannot usually be synthesized easily from inexpensive starting materials, limiting their utility. Herein, we describe the first… read more here.

Keywords: nanocage; gram scale; cage4; synthesis covalent ... See more keywords

Highly Sensitive Capsaicin Electrochemical Sensor Based on Bimetallic Metal-Organic Framework Nanocage

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Published in 2022 at "Frontiers in Chemistry"

DOI: 10.3389/fchem.2022.822619

Abstract: The content of capsaicin can be used as exotic markers of kitchen recycled oil. In this study, a bimetallic MOF nanocage (FeIII-HMOF-5) was successfully prepared by a one-step solvothermal method and used for electrode modification… read more here.

Keywords: nanocage; electrochemical sensor; highly sensitive; sensitive capsaicin ... See more keywords