One-Pot Identification of BCR/ABLp210 Transcript Isoforms Based on Nanocluster Beacon.
Sign Up to like & getrecommendations! Published in 2021 at "ACS sensors"
DOI: 10.1021/acssensors.1c00695
Abstract: The BCR/ABLp210 fusion gene is a classic biomarker of chronic myeloid leukemia, which can be divided into e13a2 and e14a2 isoforms according to different breakpoints. These two isoforms showed distinct differences in clinical manifestation, treatment… read more here.
Keywords: nanocluster beacon; one pot; bcr ablp210; based nanocluster ... See more keywords
Improving NanoCluster Beacon performance by blocking the unlabeled NC probes.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c8cc08291j
Abstract: While NanoCluster Beacon (NCB) is a versatile molecular probe, it suffers from a low target-specific signal issue due to impurities. Here we show that adding a "blocker" strand to the reaction can effectively block the… read more here.
Keywords: performance blocking; improving nanocluster; blocking unlabeled; beacon ... See more keywords