Dendrimer–didox nanocomplex for enhanced anticancer activity
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-020-04802-0
Abstract: Didox (DX; 3,4-dihydroxy benzo-hydroxamic acid), a derivative of hydroxamic acid, is a potent inhibitor of ribonucleotide reductase (RR), the enzyme responsible for deoxyribonucleotide synthesis. While RR inhibitors such as hydroxyurea and others are being used… read more here.
Keywords: didox nanocomplex; dendrimer; didox; dendrimer didox ... See more keywords
A multifunctional nanocomplex for enhanced cell uptake, endosomal escape and improved cancer therapeutic effect.
Sign Up to like & getrecommendations! Published in 2017 at "Nanomedicine"
DOI: 10.2217/nnm-2017-0034
Abstract: AIM To evaluate the chemotherapeutic potential of a novel multifunctional nanocomposite encapsulating both porous silicon (PSi) and gold (Au) nanoparticles in a polymeric nanocomplex. MATERIALS & METHODS The nanocomposite was physicochemically characterized and evaluated in… read more here.
Keywords: multifunctional nanocomplex; escape; effect; nanocomplex enhanced ... See more keywords