Miniaturized weak affinity chromatography for ligand identification of nanodiscs-embedded G-protein coupled receptors.
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DOI: 10.1016/j.aca.2020.03.062
Abstract: Biophysical techniques that enable the screening and identification of weak affinity fragments against a target protein are at the heart of Fragment Based Drug Design approaches. In the case of membrane proteins, the crucial criteria… read more here.
Keywords: protein; affinity; weak affinity; nanodiscs embedded ... See more keywords