Development of nanodispersion-based sildenafil metered-dose inhalers stabilized by poloxamer 188: a potential candidate for the treatment of pulmonary arterial hypertension
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DOI: 10.1080/10837450.2019.1650766
Abstract: Abstract Objectives: This study aims to formulate nanodispersion-based sildenafil metered-dose inhalers (MDIs) by using poloxamer 188 (P188) as a stabilizer; to evaluate their stability, aerosol characteristics, cytotoxicity, and inflammatory effects; and to investigate the effects… read more here.
Keywords: nanodispersion based; sildenafil; based sildenafil; metered dose ... See more keywords