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   Articles with "nanoemulsifying drug" as a keyword



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Formulation and biopharmaceutical evaluation of supersaturatable self‐nanoemulsifying drug delivery systems containing silymarin

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recommendations! Published in 2019 at "International Journal of Pharmaceutics"

DOI: 10.1016/j.ijpharm.2018.11.036

Abstract: Graphical abstract Figure. No caption available. Abstract The first objective of this study was to optimize a supersaturatable self‐nanoemulsifying drug delivery system (S‐SNEDDS) containing silymarin through the investigation of the single and synergistic effect of… read more here.

Keywords: silymarin; nanoemulsifying drug; drug delivery; containing silymarin ... See more keywords
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A comprehensive study of the basic formulation of supersaturated self-nanoemulsifying drug delivery systems (SNEDDS) of albendazolum

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recommendations! Published in 2021 at "Drug Delivery"

DOI: 10.1080/10717544.2021.1986601

Abstract: Abstract Albendazolum (ABZ) is a BCS class II drug. It has challenging biopharmaceutical properties, which include poor solubility and dissolution rate. These properties have laid the ground for developing a supersaturated self-nanoemulsifying drug delivery system… read more here.

Keywords: supersaturated self; nanoemulsifying drug; drug delivery; drug ... See more keywords
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Enhanced dissolution and bioavailability of revaprazan using self-nanoemulsifying drug delivery system

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recommendations! Published in 2022 at "Pharmaceutical Development and Technology"

DOI: 10.1080/10837450.2022.2070644

Abstract: Abstract A self-nanoemulsifying drug delivery system (SNEDDS) was developed to enhance the dissolution and oral bioavailability (BA) of revaprazan (RVP). Various SNEDDSs containing 200 mg of RVP were formulated using Capmul MCM, Tween 80, and Brij… read more here.

Keywords: self nanoemulsifying; dissolution; bioavailability revaprazan; delivery system ... See more keywords

From nanoemulsions to self-nanoemulsions, with recent advances in self-nanoemulsifying drug delivery systems (SNEDDS)

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recommendations! Published in 2017 at "Expert Opinion on Drug Delivery"

DOI: 10.1080/17425247.2016.1218462

Abstract: ABSTRACT Introduction: Lipid-based drug delivery systems (LBDDS) are the most promising technique to formulate the poorly water soluble drugs. Nanotechnology strongly influences the therapeutic performance of hydrophobic drugs and has become an essential approach in… read more here.

Keywords: nanoemulsifying drug; drug delivery; delivery systems; drug ... See more keywords
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Solidification of cinnarizine self-nanoemulsifying drug delivery systems by fluid bed coating: optimization of the process and formulation variables.

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recommendations! Published in 2017 at "Die Pharmazie"

DOI: 10.1691/ph.2017.6089

Abstract: Self-nanoemulsifying drug delivery systems (SNEDDS) offer an efficient choice to improve the poor dissolution and erratic bioavailability of poorly-water soluble drugs. However, liquid SNEDDS experience some manufacturing and stability limitations. To overcome these limitations, the… read more here.

Keywords: drug delivery; liquid snedds; nanoemulsifying drug; self nanoemulsifying ... See more keywords
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Improved Pharmacodynamic Potential of Rosuvastatin by Self-Nanoemulsifying Drug Delivery System: An in vitro and in vivo Evaluation

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recommendations! Published in 2021 at "International Journal of Nanomedicine"

DOI: 10.2147/ijn.s287665

Abstract: Purpose The purpose of this proposed research was to investigate a nano-formulation developed using self-nanoemulsifying drug delivery system (SNEDDS) to improve the pharmacodynamic potential of rosuvastatin by assisting its transportation through lymphatic circulation. Methods The… read more here.

Keywords: formulation; self nanoemulsifying; nanoemulsifying drug; drug ... See more keywords

Evaluation of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Poorly Water-Soluble Talinolol: Preparation, in vitro and in vivo Assessment

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recommendations! Published in 2019 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2019.00459

Abstract: Objective The aim of this study was to investigate the in vitro and in vivo performance of self-nanoemulsifying drug delivery systems (SNEDDSs) of talinolol (TAL), a poorly water-soluble drug. Methods Self-nanoemulsifying drug delivery systems of… read more here.

Keywords: nanoemulsifying drug; drug delivery; delivery systems; water soluble ... See more keywords
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Preparation and Evaluation of a Self-Nanoemulsifying Drug Delivery System Loaded with Heparin Phospholipid Complex

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recommendations! Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22084077

Abstract: A self-nanoemulsifying drug delivery system (SNEDDS) was developed to enhance the absorption of heparin after oral administration, in which heparin was compounded with phospholipids to achieve better fat solubility in the form of heparin-phospholipid (HEP-Pc)… read more here.

Keywords: heparin; nanoemulsifying drug; delivery system; drug delivery ... See more keywords
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Self-Nanoemulsifying Drug Delivery System (SNEDDS) of Apremilast: In Vitro Evaluation and Pharmacokinetics Studies

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recommendations! Published in 2022 at "Molecules"

DOI: 10.3390/molecules27103085

Abstract: Psoriatic arthritis is an autoimmune disease of the joints that can lead to persistent inflammation, irreversible joint damage and disability. The current treatments are of limited efficacy and inconvenient. Apremilast (APR) immediate release tablets Otezla®… read more here.

Keywords: self nanoemulsifying; delivery system; nanoemulsifying drug; drug delivery ... See more keywords
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Optimization of a Cefuroxime Axetil-Loaded Liquid Self-Nanoemulsifying Drug Delivery System: Enhanced Solubility, Dissolution and Caco-2 Cell Uptake

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recommendations! Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14040772

Abstract: Cefuroxime axetil (CA) is an oral cephalosporin which hydrolyzes rapidly to the active parent compound cefuroxime. CA is known to have incomplete oral bioavailability (30–50%) due to its poor solubility and enzymatic conversion to cefuroxime… read more here.

Keywords: self nanoemulsifying; cefuroxime axetil; solubility; cefuroxime ... See more keywords

Design development and evaluation of self nanoemulsifying drug delivery system of simvastatin

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recommendations! Published in 2018 at "Research Journal of Pharmacy and Technology"

DOI: 10.5958/0974-360x.2018.00221.4

Abstract: The aim of this work was to improve the invitro dissolution of Simvastatin through development of self nanoemulsifying capsules. Simvastatin is a poorly-water soluble drug and cholesterol lowering agent. It has poor oral bioavailability (5%)… read more here.

Keywords: nanoemulsifying drug; drug delivery; simvastatin; drug ... See more keywords