Codelivery of 1α,25-Dihydroxyvitamin D3 and CYP24A1 Inhibitor VID400 by Nanofiber Dressings Promotes Endogenous Antimicrobial Peptide LL-37 Induction.
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DOI: 10.1021/acs.molpharmaceut.1c00944
Abstract: Surgical site infections represent a significant clinical problem. Herein, we report a nanofiber dressing for topical codelivery of immunomodulating compounds including 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) and VID400, a CYP24A1 inhibitor in a sustained manner, for inducing… read more here.
Keywords: nanofiber dressings; vid400 coencapsulated; vid400; antimicrobial peptide ... See more keywords
Electrospun Chitosan–Polyvinyl Alcohol Nanofiber Dressings Loaded with Bioactive Ursolic Acid Promoting Diabetic Wound Healing
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DOI: 10.3390/nano12172933
Abstract: The design and development of novel dressing materials are urgently required for the treatment of chronic wounds caused by diabetic ulcers in clinics. In this study, ursolic acid (UA) extracted from Chinese herbal plants was… read more here.
Keywords: nanofiber dressings; polyvinyl alcohol; ursolic acid; diabetic wound ... See more keywords