Inhaled mRNA Nanoformulation with Biogenic Ribosomal Protein Reverses Established Pulmonary Fibrosis in a Bleomycin‐Induced Murine Model
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202107506
Abstract: Idiopathic pulmonary fibrosis (IPF), a lethal respiratory disease with few treatment options, occurs due to repetitive microinjuries to alveolar epithelial cells (AECs) and progresses with an overwhelming deposition of extracellular matrix (ECM), ultimately resulting in… read more here.
Keywords: ribosomal protein; bleomycin induced; pulmonary fibrosis; mrna nanoformulation ... See more keywords
A Multifunctional Photoacoustic/Fluorescence Dual‐Mode‐Imaging Gold‐Based Theranostic Nanoformulation without External Laser Limitations
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202110690
Abstract: Theranostics is a new type of biomedical technology that organically combines the diagnosis and therapy of diseases. Among molecular imaging techniques, the integration of photoacoustic (PA) and fluorescence (FL) imaging modes with high sensitivity and… read more here.
Keywords: photoacoustic fluorescence; dual mode; external laser; nanoformulation ... See more keywords
Lethal Effect and Behavioral Responses of Leaf-Cutting Ants to Essential Oil of Pogostemon cablin (Lamiaceae) and Its Nanoformulation
Sign Up to like & getrecommendations! Published in 2018 at "Neotropical Entomology"
DOI: 10.1007/s13744-018-0615-6
Abstract: Leaf-cutting ants belonging to the genus Atta (Formicidae: Myrmicinae) are important pests in agricultural and forest environments. In the present study, we evaluated the formicidal activity of the essential oil of Pogostemon cablin and its… read more here.
Keywords: essential oil; cablin; leaf cutting; nanoformulation ... See more keywords
Precise nano-programmed ferroptosis with enhanced tumor chemotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Science China Materials"
DOI: 10.1007/s40843-020-1410-x
Abstract: Cancer treatment is one of the greatest challenges in biomedical research, and the development of novel tumor-inhibition mechanisms has long been a topic of interest for researchers in this field. Ferroptosis is one such candidate… read more here.
Keywords: chemotherapy; nanoformulation; ferroptosis; dox ... See more keywords
Green synthesis of silver nanoformulation of Scindapsus officinalis as potent anticancer and predicted anticovid alternative: Exploration via experimental and computational methods
Sign Up to like & getrecommendations! Published in 2021 at "Biocatalysis and Agricultural Biotechnology"
DOI: 10.1016/j.bcab.2021.102072
Abstract: Abstract The current study was focused on the investigation of anticancer activity of Scindapsus Officinalis fruit extract embedded silver nanoparticles (So-AgNPs) followed by anticovid activity prognosis of major phytocompounds, which participate in nanoformulation synthesis. The… read more here.
Keywords: scindapsus officinalis; silver; nanoformulation; anticancer ... See more keywords
ST8 micellar/niosomal vesicular nanoformulation for delivery of naproxen in cancer cells: Physicochemical characterization and cytotoxicity evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.127867
Abstract: Abstract Naproxen (NPX) is a non-steroidal anti-inflammatory drug (NSAID) used against a variety of diseases, including autoimmune disorders and chronic inflammations. However, low water solubility limits its therapeutic efficacy and novel nanoformulations are required to… read more here.
Keywords: st8 micellar; micellar niosomal; delivery; nanoformulation ... See more keywords
Intratumoral Anti-PD-1 Nanoformulation Improves Its Biodistribution.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c22479
Abstract: Intratumoral administration of immune checkpoint inhibitors, such as programmed cell death-1 antibodies (aPD-1), is a promising approach toward addressing both the low patients' responses and high off-target toxicity, but good preclinical results have not translated… read more here.
Keywords: free apd; intratumoral administration; intratumoral anti; apd ... See more keywords
Nanoformulation of Curcuma longa Root Extract and Evaluation of Its Dissolution Potential
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DOI: 10.1021/acsomega.2c06258
Abstract: Medicinal plants have been widely used for therapeutic purposes for a long time, but they have been found to have some major issues such as low water solubility and bioavailability. In the present study, the… read more here.
Keywords: curcuma longa; dissolution; nanoformulation curcuma; dissolution potential ... See more keywords
Pluronic Polymer-Based Ormeloxifene Nanoformulations Induce Superior Anticancer Effects in Pancreatic Cancer Cells
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.9b03382
Abstract: Utilization of safe cytotoxic agents with precise anticancer activity is considered as the prime focus of cancer therapeutics research. A greater incentive for such agents arises from the molecules/drugs that are already being used for… read more here.
Keywords: nanoformulation; pluronic polymer; polymer based; cancer ... See more keywords
Nanoformulation of Lipophilic Osmium Photosensitizers in Liposomes and Micelles as a General Strategy for Improving Reproducibility and Reducing Quenching †
Sign Up to like & getrecommendations! Published in 2023 at "Photochemistry and Photobiology"
DOI: 10.1111/php.13776
Abstract: Nanoformulation of an osmium photosensitizer within liposomes and micelles is used to improve the water‐solubility of this highly lipophilic molecule. This highlight report describes a recent paper by Cameron, Obaid and McFarland on this topic… read more here.
Keywords: nanoformulation lipophilic; strategy; lipophilic osmium; liposomes micelles ... See more keywords
Nanoformulation of PROteolysis TArgeting Chimera targeting 'undruggable' c-Myc for the treatment of pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Nanomedicine"
DOI: 10.2217/nnm-2020-0156
Abstract: Aim: To explore the anticancer activity of a novel BRD4 protein degrader ARV-825 (ARV) and its nanoformulation development (ARV-NP) for treatment of pancreatic cancer. Materials & methods: ARV-NP were prepared using nanoprecipitation method and characterized… read more here.
Keywords: nanoformulation; pancreatic cancer; cancer; treatment pancreatic ... See more keywords