Stereospecific NANOG PEST Stabilization by Pin1.
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DOI: 10.1021/acs.biochem.4c00056
Abstract: NANOG protein levels correlate with stem cell pluripotency. NANOG concentrations fluctuate constantly with low NANOG levels leading to spontaneous cell differentiation. Previous literature implicated Pin1, a phosphorylation-dependent prolyl isomerase, as a key player in NANOG… read more here.
Keywords: pin1; stereospecific nanog; nanog pest; pest stabilization ... See more keywords