Myelosuppression caused by nanoparticle albumin-bound paclitaxel in the Northern Chinese population and the role of body composition.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of clinical pharmacology"
DOI: 10.1002/jcph.2259
Abstract: To examine the relationship between lean body mass (LBM) and the incidence and severity of neutropenia in patients with malignant tumors from Northern China who have received nanoparticle albumin-bound paclitaxel. Twenty-six patients with pathologically confirmed… read more here.
Keywords: albumin bound; incidence; group; bound paclitaxel ... See more keywords
Carboplatin plus weekly nanoparticle albumin-bound paclitaxel in elderly patients with previously untreated advanced squamous non-small-cell lung cancer selected based on Mini Nutritional Assessment short-form scores: a multicenter phase 2 study
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-017-3385-7
Abstract: PurposeThis multicenter, single-arm, open-label, phase 2 study assessed the efficacy and safety of carboplatin plus weekly nanoparticle albumin-bound paclitaxel in elderly patients with previously untreated advanced squamous non-small-cell lung cancer, selected based on the Mini… read more here.
Keywords: plus weekly; nanoparticle albumin; bound paclitaxel; cancer ... See more keywords
Nanoparticle albumin-bound paclitaxel: a big nano for the treatment of gastric cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03887-2
Abstract: Gastric cancer (GC) is the third cause of cancer-related death worldwide. Patients with unresectable GC can be treated with chemotherapy such as paclitaxel, which is a microtubule stabilizer. The use of nanoparticle albumin-bound paclitaxel (nab-ptx)… read more here.
Keywords: nanoparticle albumin; gastric cancer; bound paclitaxel; cancer ... See more keywords
Scanning Electron-Raman Cryomicroscopy for Characterization of Nanoparticle-Albumin Drug Products.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03826
Abstract: Nanomaterials have expanded the use of active pharmaceutical ingredients by improving efficacy, decreasing toxicity, and facilitating targeted delivery. To systematically achieve this goal, nanomaterial-containing drugs need to be manufactured with precision in attributes such as… read more here.
Keywords: chemistry; electron raman; scanning electron; characterization ... See more keywords
S-1 and oxaliplatin combined with nanoparticle albumin-bound paclitaxel adjuvant chemotherapy for advanced gastric adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002003
Abstract: To the Editor: Gastric cancer (GC) is the fi fth most common malignancy and the third most common cause of cancer-related death worldwide, with > 70% cases occurring in Asian populations. [1 read more here.
Keywords: albumin bound; combined nanoparticle; oxaliplatin combined; paclitaxel adjuvant ... See more keywords
The efficacy and safety of nanoparticle albumin bound‐paclitaxel‐based regimen as second‐ or third‐line treatment in patients with advanced esophageal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.14885
Abstract: There are limited reports on nanoparticle albumin bound‐paclitaxel (nab‐paclitaxel) regimens as second‐ or third‐line treatments for advanced esophageal squamous cell carcinoma (ESCC). Additionally, its safety and efficacy in ESCC patients after failure of first‐line programmed… read more here.
Keywords: albumin bound; cell; efficacy; line ... See more keywords
Phase I Study of Combination Therapy With Weekly Nanoparticle Albumin-bound Paclitaxel and Cyclophosphamide in Metastatic Breast Cancer Patients
Sign Up to like & getrecommendations! Published in 2019 at "AntiCancer Research"
DOI: 10.21873/anticanres.13910
Abstract: Background/Aim: The objective of this phase I study was to determine the maximum-tolerated dose (MTD) and recommended dose (RD) of combination therapy with weekly nanoparticle albumin-bound paclitaxel (nab-paclitaxel) and cyclophosphamide (CPA) in metastatic breast cancer… read more here.
Keywords: nanoparticle albumin; therapy weekly; weekly nanoparticle; phase study ... See more keywords