Biomedical nanoparticle design: What we can learn from viruses
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2020.09.045
Abstract: Viruses are nanomaterials with a number of properties that surpass those of many synthetic nanoparticles (NPs) for biomedical applications. They possess a rigorously ordered structure, come in a variety of shapes, and present unique surface… read more here.
Keywords: nanoparticle design; design learn; learn viruses; biomedical nanoparticle ... See more keywords
Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Society reviews"
DOI: 10.1039/c6cs00592f
Abstract: Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared with normal tissue, the tumour microenvironment has some unique properties, such as vascular abnormalities, hypoxia and acidic pH. There are many types of… read more here.
Keywords: microenvironment; nanoparticle design; exploiting tumour; therapy ... See more keywords
Gold nanoparticle design for RNA compaction.
Sign Up to like & getrecommendations! Published in 2022 at "Biointerphases"
DOI: 10.1116/6.0002043
Abstract: RNA-based therapeutics hold a great promise in treating a variety of diseases. However, double-stranded RNAs (dsRNAs) are inherently unstable, highly charged, and stiff macromolecules that require a delivery vehicle. Cationic ligand functionalized gold nanoparticles (AuNPs)… read more here.
Keywords: nanoparticle design; rna; design rna; major groove ... See more keywords