A Polymeric Nanoparticle Formulation for Targeted mRNA Delivery to Fibroblasts
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202205475
Abstract: Messenger RNA (mRNA)‐based therapies offer enhanced control over the production of therapeutic proteins for many diseases. Their clinical implementation warrants formulations capable of delivering them safely and effectively to target sites. Owing to their chemical… read more here.
Keywords: nanoparticle formulation; delivery; mrna delivery; polymeric nanoparticle ... See more keywords
Nanoparticle Formulation Derived from Carboxymethyl Cellulose, Polyethylene Glycol, and Cabazitaxel for Chemotherapy Delivery to the Brain.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.8b00220
Abstract: Nanoparticles provide a unique opportunity to explore the benefits of selective distribution and release of cancer therapeutics at sites of disease through varying particle sizes and compositions that exploit the enhanced permeability of tumor-associated blood… read more here.
Keywords: delivery; nanoparticle; carboxymethyl cellulose; nanoparticle formulation ... See more keywords
Abstract 4658: Novel paclitaxel medical nanoparticle formulation for breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-4658
Abstract: Objectives: Paclitaxel (Ptxl) is currently the most common first-line therapeutic option for breast cancer (BrCa). However, adverse side effects and problems associated with chemo-resistance, limits its use in clinical settings. Nanoparticle mediated delivery can improve… read more here.
Keywords: formulation; breast cancer; nanoparticle formulation; cancer ... See more keywords
New Nanoparticle Formulation for Cyclosporin A: In Vitro Assessment
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DOI: 10.3390/pharmaceutics13010091
Abstract: Cyclosporin A (CsA) is a molecule with well-known immunosuppressive properties. As it also acts on the opening of mitochondrial permeability transition pore (mPTP), CsA has been evaluated for ischemic heart diseases (IHD). However, its distribution… read more here.
Keywords: cyclosporin; sqcsa nps; nanoparticle formulation; new nanoparticle ... See more keywords
LC/MS Profiling and Gold Nanoparticle Formulation of Major Metabolites from Origanum majorana as Antibacterial and Antioxidant Potentialities
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11141871
Abstract: Origanum majoranum L. is a Lamiaceae medicinal plant with culinary and ethnomedical applications. Its biological and phytochemical profiles have been extensively researched. Accordingly, this study aimed to investigate the chemical composition and the antibacterial and… read more here.
Keywords: antibacterial antioxidant; nanoparticle formulation; antioxidant; profiling gold ... See more keywords