Trehalose Conjugated, Catechin Loaded Polylactide Nanoparticle for Improved Neuroprotection against Intracellular Polyglutamine Aggregate.
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DOI: 10.1021/acs.biomac.0c00143
Abstract: Intracellular/extracellular protein aggregation is linked to variety of neurodegenerative diseases. Current research focusses on identifying anti-amyloidogenic small molecules to inhibit such protein aggregation and associated cytotoxicity. We have recently demonstrated that transforming those anti-amyloidogenic small… read more here.
Keywords: aggregation; nanoparticle improved; improved neuroprotection; nanoparticle ... See more keywords