Peptide-functionalized nanoparticles for brain-targeted therapeutics.
Sign Up to like & getrecommendations! Published in 2025 at "Drug delivery and translational research"
DOI: 10.1007/s13346-025-01840-w
Abstract: Despite the rapid development of nanoparticle (NP)-based drug delivery systems, intravenous delivery of drugs to the brain remains a major challenge due to various biological barriers. To achieve therapeutic effects, NP-encapsulated drugs must avoid accumulation… read more here.
Keywords: brain targeted; brain; peptide functionalized; nanoparticles brain ... See more keywords
The effect of dose and selection of two different ligands on the deposition and antitumor efficacy of targeted nanoparticles in brain tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.9b00693
Abstract: Deposition of nanoparticles to tumors often can be enhanced by targeting receptors overexpressed in a tumor. However, a tumor may exhibit a finite number of a biomarker that is accessible and targetable by nanoparticles, limiting… read more here.
Keywords: nanoparticles brain; deposition; drug; brain tumors ... See more keywords
Formulations of Curcumin Nanoparticles for Brain Diseases
Sign Up to like & getrecommendations! Published in 2019 at "Biomolecules"
DOI: 10.3390/biom9020056
Abstract: Curcumin is a polyphenol that is obtained from Curcuma longa and used in various areas, such as food and textiles. Curcumin has important anti-inflammatory and antioxidant properties that allow it to be applied as treatment… read more here.
Keywords: nanoparticles brain; formulations curcumin; brain diseases; curcumin nanoparticles ... See more keywords
Angiopep-2-Modified Nanoparticles for Brain-Directed Delivery of Therapeutics: A Review
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14040712
Abstract: Nanotechnology has opened up a world of possibilities for the treatment of brain disorders. Nanosystems can be designed to encapsulate, carry, and deliver a variety of therapeutic agents, including drugs and nucleic acids. Nanoparticles may… read more here.
Keywords: angiopep modified; delivery; nanoparticles brain; modified nanoparticles ... See more keywords