Lipid Nanoparticles for Broad‐Spectrum Nucleic Acid Delivery
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DOI: 10.1002/adfm.202101391
Abstract: Lipid nanoparticles (LNPs) are the most advanced nonviral modality for nucleic acid (NA) delivery, and have recently gained enormous attention in the fields of RNA therapeutics and vaccine development. Here, ionizable adamantane‐based lipidoids named XMaNs,… read more here.
Keywords: lipid nanoparticles; delivery; acid delivery; nanoparticles broad ... See more keywords
Tapered chiral nanoparticles as broad-spectrum thermally stable antivirals for SARS-CoV-2 variants
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2310469121
Abstract: Significance The Achilles heel of the best available antiviral mRNA vaccines and biomolecular drugs includes the loss of their potency due to viral mutations and thermal exposure. Chiral L- or D-penicillamine-coated CuS nanoparticles (NPs) provide… read more here.
Keywords: sars cov; broad spectrum; chiral nanoparticles; cov variants ... See more keywords