Optimizing Lipid Nanoparticles for Delivery in Primates.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202211420
Abstract: Lipid nanoparticles (LNPs) are clinically proven to successfully deliver both small interfering RNA (siRNA) therapeutics and larger mRNA payloads for prophylactic vaccine applications. Non-human primates (NHPs) are generally considered to be the most predictive of… read more here.
Keywords: nanoparticles delivery; potency; optimizing lipid; delivery primates ... See more keywords
Advances of biological-camouflaged nanoparticles delivery system
Sign Up to like & getrecommendations! Published in 2020 at "Nano Research"
DOI: 10.1007/s12274-020-2931-5
Abstract: Nanoparticles (NPs) which are innovation and research focus in drug delivery systems, still have some disadvantages limiting its application in clinical use, such as short circulation time, recognition and clearance by reticuloendothelial system (RES) and… read more here.
Keywords: camouflaged nanoparticles; nanoparticles delivery; advances biological; system ... See more keywords
Retracted: Mannosylated Chitosan Nanoparticles for Delivery of Antisense Oligonucleotides for Macrophage Targeting
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/1878130
Abstract: [This retracts the article DOI: 10.1155/2014/526391.]. read more here.
Keywords: retracted mannosylated; nanoparticles delivery; delivery antisense; chitosan nanoparticles ... See more keywords
Lipid Nanoparticles as Delivery Vehicles for Inhaled Therapeutics
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DOI: 10.3390/biomedicines10092179
Abstract: Lipid nanoparticles (LNPs) have emerged as a powerful non-viral carrier for drug delivery. With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 pandemic, investigations into applying LNPs to deliver inhaled therapeutics directly… read more here.
Keywords: nanoparticles delivery; lipid nanoparticles; delivery; vehicles inhaled ... See more keywords
Lipid nanoparticles for delivery of RNA therapeutics: Current status and the role of in vivo imaging
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.77259
Abstract: Lipid nanoparticles (LNPs) have been one of the most successful nano-delivery vehicles that enable efficient delivery of cytotoxic chemotherapy agents, antibiotics, and nucleic acid therapeutics. During the coronavirus disease (COVID-19) pandemic, LNP-based COVID-19 messenger RNA… read more here.
Keywords: nanoparticles delivery; lnp based; rna therapeutics; delivery ... See more keywords