Coated Lipidic Nanoparticles as a New Strategy for Enhancing Nose-to-Brain Delivery of a Hydrophilic Drug Molecule.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.04.007
Abstract: Oral Almotriptan maleate (ALM) is used in the treatment of migraine; however, due to its extreme aqueous solubility, shows poor penetration and lesser concentration in the brain thus requiring frequent oral dosing. Being flexible and… read more here.
Keywords: coated lipidic; lipidic nanoparticles; drug; nanoparticles new ... See more keywords
Exosome-Like Nanoparticles: A New Type Of Nanocarrier.
Sign Up to like & getrecommendations! Published in 2019 at "Current medicinal chemistry"
DOI: 10.2174/0929867326666190129142604
Abstract: Nanoparticles are one of the most used systems for imaging or therapeutic drug delivery. Exosomes are nanovesicular carriers that transport cargo for intercellular communication. These nanovesicles are linked to the pathology of some major diseases,… read more here.
Keywords: like nanoparticles; new type; type nanocarrier; exosome like ... See more keywords
Metallic Nanoparticles: A New Frontier in the Fight Against Leishmaniasis.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220225111052
Abstract: Leishmaniasis is a cutaneous, mucocutaneous, or visceral parasitic disease caused by protozoa of the Leishmania genus. According to the World Health Organization, Leishmaniasis causes approximately 20-40 thousand deaths annually, and Brazil, India, and some countries… read more here.
Keywords: new frontier; metallic nanoparticles; fight leishmaniasis; leishmaniasis ... See more keywords
Nanoparticles in the New Era of Cardiovascular Therapeutics: Challenges and Opportunities
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065205
Abstract: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Although a cadre of therapeutic strategies have been made available for CVDs in the clinical setting, predominantly through medication and surgery, these do… read more here.
Keywords: therapeutics challenges; era cardiovascular; challenges opportunities; nanoparticles new ... See more keywords