What's Next after Lipid Nanoparticles? A Perspective on Enablers of Nucleic Acid Therapeutics.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00058
Abstract: Recent success of mRNA-based COVID-19 vaccines have bolstered the strength of nucleic acids as a therapeutic platform. The number of new clinical trial candidates is skyrocketing with the potential to address many unmet clinical needs.… read more here.
Keywords: nucleic acid; next lipid; perspective enablers; enablers nucleic ... See more keywords
Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies.
Sign Up to like & getrecommendations! Published in 2020 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.0c00075
Abstract: Engineered nanoparticles (NPs) to specifically deliver payload therapeutics to target cells involved in pathophysiological processes seem to offer a powerful strategy to overcome intrinsic limitations of drugs. In this Viewpoint we disclose the synergistic potential… read more here.
Keywords: targeted nanoparticles; perspective nanotherapies; chemistry; potential targeted ... See more keywords