Targeted lipid nanoparticles for RNA therapeutics and immunomodulation in leukocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2020.04.002
Abstract: Abnormalities in leukocytes' function are associated with many immune related disorders, such as cancer, autoimmunity and susceptibility to infectious diseases. Recent developments in Genome-wide-association-studies give rise to new opportunities for novel therapeutics. RNA-based modalities, that… read more here.
Keywords: targeted lipid; nanoparticles rna; rna therapeutics; rna based ... See more keywords
Multicomponent Lipid Nanoparticles for RNA Transfection
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DOI: 10.3390/pharmaceutics15041289
Abstract: Despite the wide variety of available cationic lipid platforms for the delivery of nucleic acids into cells, the optimization of their composition has not lost its relevance. The purpose of this work was to develop… read more here.
Keywords: rna transfection; lnps; nanoparticles rna; multicomponent lipid ... See more keywords