Bio-Responsive Macromolecular Drug and Small-Molecular Drug Conjugates: Nanoparticulate Prodrugs for Tumor Microenvironment Heterogeneity Management and Therapeutic Response Enhancement.
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DOI: 10.1002/smll.202301656
Abstract: How to break through the poor response of current drug therapy, which often resulted from tumor microenvironment heterogeneity (TMH), remains an enormous challenge in the treatment of critical diseases. In this work, a practical solution… read more here.
Keywords: nanoparticulate prodrugs; drug conjugates; tumor microenvironment; small molecular ... See more keywords