Developing Acid‐Responsive Glyco‐Nanoplatform Based Vaccines for Enhanced Cytotoxic T‐lymphocyte Responses Against Cancer and SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202105059
Abstract: Abstract Cytotoxic T‐lymphocytes (CTLs) are central for eliciting protective immunity against malignancies and infectious diseases. Here, for the first time, partially oxidized acetalated dextran nanoparticles (Ox‐AcDEX NPs) with an average diameter of 100 nm are… read more here.
Keywords: nanoplatform; acdex imine; acdex; acdex nps ... See more keywords
Temperature-dependent CAT-like RGD-BPNS@SMFN Nanoplatform for PTT-PDT self-synergetic Tumor Phototherapy.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202102298
Abstract: Phototherapies such as photothermal therapy (PTT) and photodynamic therapy (PDT) are considered as alternatives for tumor remedies, because of their advantages of precise spatial orientation, minimally invasive and nonradiative operation. However, most of phototherapeutic agents… read more here.
Keywords: cat like; pdt self; ptt pdt; self synergetic ... See more keywords
An mTOR siRNA‐Loaded Spermidine/DNA Tetrahedron Nanoplatform with a Synergistic Anti‐Inflammatory Effect on Acute Lung Injury (Adv. Healthcare Mater. 11/2022)
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200008
Abstract: Acute lung injury (ALI) is characterized by severe inflammation and damage to the lung air-blood barrier, resulting in respiratory function damage and life-threatening outcomes. Macrophage polarization plays an essential role in the occurrence, development, and… read more here.
Keywords: acute lung; dna; lung injury; anti inflammatory ... See more keywords
Duplex Responsive Nanoplatform with Cascade Targeting for Atherosclerosis Photoacoustic Diagnosis and Multichannel Combination Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202300439
Abstract: The culprits of atherosclerosis are endothelial damage, local disorders of lipid metabolism, and progressive inflammation. Early atherosclerosis is typically difficult to diagnose in time due to the lack of obvious symptoms, thus missing the best… read more here.
Keywords: pmetpp mbt; duplex responsive; photoacoustic diagnosis; atherosclerosis ... See more keywords
Near Infrared-Triggered Theranostic Nanoplatform with Controlled Release of HSP90 Inhibitor for Synergistic Mild Photothermal and Enhanced Nanocatalytic Therapy with Hypoxia Relief.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200786
Abstract: Mild photothermal therapy (PTT, 50 °C). However, its therapeutic efficacy is limited owing to the hypoxic tumor environment and tumor thermoresistance owing to the overproduction of heat shock proteins (HSPs). Herein, a near-infrared (NIR)-triggered theranostic nanoplatform… read more here.
Keywords: hsp90; therapy; triggered theranostic; mild photothermal ... See more keywords
Multifunctional Hollow MnO2 @Porphyrin@Bromelain Nanoplatform for Enhanced Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202204951
Abstract: Photodynamic therapy (PDT) has been showing great potential in cancer treatment. However, the efficacy of PDT is always limited by the intrinsic hypoxic tumor microenvironment (TME) and the low accumulation efficiency of photosensitizers in tumors.… read more here.
Keywords: mno2; tpyp; therapy; multifunctional hollow ... See more keywords
A tumor microenvironment responsive nanoplatform with oxidative stress amplification for effective MRI-based visual tumor ferroptosis.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.11.007
Abstract: As a promising new form of non-apoptotic regulated cell death, ferroptosis has potential as an effective supplement to apoptosis-based cancer treatments. However, high intracellular glutathione (GSH) levels and insufficient hydrogen peroxide (H2O2) in the tumor… read more here.
Keywords: nanoplatform; mri based; ferroptosis; based visual ... See more keywords
ROS-augmented and tumor-microenvironment responsive biodegradable nanoplatform for enhancing chemo-sonodynamic therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.119761
Abstract: Nanocarrier for augmenting the efficacy of reactive oxygen species (ROS) by tumor microenvironment (TME) has become an emerging strategy for cancer treatment. Herein, a smart biodegradable drug delivery nanoplatform with mitochondrial-targeted ability, pH-responsive drug release… read more here.
Keywords: tumor microenvironment; nanoplatform; sonodynamic therapy; tumor ... See more keywords
Layer structured LDH_ZnPcG4-FA nanoplatform for targeted and imaging guided chemo-photodynamic therapy mediated by 650 nm light
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DOI: 10.1016/j.cej.2019.122847
Abstract: Abstract Designing a phototherapeutic material that simultaneously has target, tumor microenvironment (TME)-response, high-quality imaging and synergistic therapy has attracted much attention in anticancer field. Herein, a novel stimuli-responsive multifunctional nanoplatform has been constructed by inserting… read more here.
Keywords: znpcg4; nanoplatform; chemo photodynamic; dox ... See more keywords
Radial extracorporeal shock wave responsive precise nanoplatform for effective osteoporosis sequential treatment
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.130687
Abstract: Abstract Osteoporosis (OP), which is associated with an imbalance between osteoblasts (OBs) and osteoclasts (OCs), is sequentially treated with anabolic and anti-resorption agents in the clinic to improve outcome. However, the long duration of treatment… read more here.
Keywords: responsive precise; treatment; radial extracorporeal; extracorporeal shock ... See more keywords
pH-programmed responsive nanoplatform for synergistic cancer therapy based on single atom catalysts.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2022.114236
Abstract: The development of stimuli-responsive nanoplatform provides powerful tool for simultaneously enhancing the efficiency and accuracy of cancer therapies. Herein, we develop a pH-programmed responsive and synergistically theranostic nanoplatform based on CaCO3 mineralized single atom iron… read more here.
Keywords: cancer; responsive nanoplatform; programmed responsive; therapy ... See more keywords