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   Articles with "nanopore sensing" as a keyword



Regulation of Supramolecular Interactions: RNA:DNA Folding and Nanopore Sensing Applications

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recommendations! Published in 2025 at "ChemBioChem"

DOI: 10.1002/cbic.202500709

Abstract: The intersection of DNA/RNA nanotechnology and single‐molecule solid‐state nanopore sensing enables precise detection of low‐abundance biomolecules. However, a significant challenge persists that nucleic acid molecules readily fold during nanopore translocation, which gives rise to ambiguous… read more here.

Keywords: regulation supramolecular; supramolecular interactions; nanotechnology; rna dna ... See more keywords

Nanopore Sensing Technique for Studying the Hofmeister Effect.

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recommendations! Published in 2022 at "Small"

DOI: 10.1002/smll.202200921

Abstract: The nanopore sensing technique is an emerging method of detecting single molecules, and extensive research has gone into various fields, including nanopore sequencing and other applications of single-molecule studies. Recently, several researchers have explored the… read more here.

Keywords: technique studying; sensing technique; hofmeister effect; nanopore sensing ... See more keywords

Retarded translocation of nucleic acids through α-hemolysin nanopore in the presence of a calcium flux.

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recommendations! Published in 2020 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.0c05626

Abstract: Electrophysiological measurement of molecular translocation through a nanopore is the fundamental basis of nanopore sensing. Free translocation of nucleic acids however is normally so fast that the identities of the compounds are not clearly resolvable.… read more here.

Keywords: nucleic acids; nanopore sensing; translocation; translocation nucleic ... See more keywords

Identifying Viral Vector Characteristics by Nanopore Sensing.

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recommendations! Published in 2024 at "ACS nano"

DOI: 10.1021/acsnano.4c01888

Abstract: Using viral vectors as gene delivery vehicles for gene therapy necessitates their quality control. Here, we report on nanopore sensing for nondestructively inspecting genomes inside the nanoscale cargoes at the single-molecule level. Using ionic current… read more here.

Keywords: identifying viral; vector characteristics; gene; characteristics nanopore ... See more keywords

Nanopore Sensing of DNA-Histone Complexes on Nucleosome Arrays.

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recommendations! Published in 2022 at "ACS sensors"

DOI: 10.1021/acssensors.2c01865

Abstract: The location of nucleosomes in DNA and their structural stability are critical in regulating DNA compaction, site accessibility, and epigenetic gene regulation. Here, we combine the nanopore platform-based fast and label-free single-molecule detection technique with… read more here.

Keywords: dna; nanopore sensing; sensing dna; voltage dependent ... See more keywords
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Ligand-Induced Structural Changes of Thiolate-Capped Gold Nanoclusters Observed with Resistive-Pulse Nanopore Sensing.

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recommendations! Published in 2019 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.8b12535

Abstract: Nanopore-based resistive pulse sensing with biological nanopores has traditionally been applied to biopolymer analysis, but more recently, interest has grown in applying the technique to characterizing water-soluble metallic clusters. This paper reports on the use… read more here.

Keywords: capped gold; nanopore sensing; gold nanoclusters; thiolate capped ... See more keywords

Plasmonic Nanopore Sensing to Probe the DNA Loading Status of Adeno-Associated Viruses

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recommendations! Published in 2025 at "Chemosensors"

DOI: 10.3390/chemosensors13120418

Abstract: Adeno-associated viruses (AAVs) are a leading vector for gene therapy, yet their clinical utility is limited by the lack of robust quality control methods to distinguish between empty (AAVempty), partially loaded (AAVpartial), and fully DNA… read more here.

Keywords: adeno associated; associated viruses; status; plasmonic nanopore ... See more keywords

Localized Nanopore Fabrication via Controlled Breakdown

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recommendations! Published in 2022 at "Nanomaterials"

DOI: 10.3390/nano12142384

Abstract: Nanopore sensors provide a unique platform to detect individual nucleic acids, proteins, and other biomolecules without the need for fluorescent labeling or chemical modifications. Solid-state nanopores offer the potential to integrate nanopore sensing with other… read more here.

Keywords: nanopores formed; controlled breakdown; nanopore sensing; localized nanopore ... See more keywords