An Optically Controlled Virtual Microsensor for Biomarker Detection In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202205760
Abstract: Current technologies for the real‐time analysis of biomarkers in vivo, such as needle‐type microelectrodes and molecular imaging methods based on exogenous contrast agents, are still facing great challenges in either invasive detection or lack of… read more here.
Keywords: controlled virtual; optically controlled; virtual microsensor; detection ... See more keywords
Biodegradable Nanoprobe for NIR-II Fluorescence Image-Guided Surgery and Enhanced Breast Cancer Radiotherapy Efficacy.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202104728
Abstract: Positive resection margin frequently exists in breast-conserving treatment (BCT) of early-stage breast cancer, and insufficient therapeutic efficacy is common during radiotherapy (RT) in advanced breast cancer patients. Moreover, a multimodal nanotherapy platform is urgently required… read more here.
Keywords: breast; cancer; breast cancer; efficacy ... See more keywords
FITC characterization of a cathepsin B‐responsive nanoprobe for report of differentiation of HL60 cells into macrophages
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Peptide Science"
DOI: 10.1002/psc.3371
Abstract: A cathepsin B (Cat B)‐responsive optical nanoprobe is designed and prepared for report of HL60 differentiation into macrophage. A peptide sequence FRFK is linked to fluorescein (FITC) via the distant amino group of its lysine… read more here.
Keywords: differentiation; report; hl60 cells; cathepsin ... See more keywords
Development of a near infrared protein nanoprobe targeting Thomsen-Friedenreich antigen for intraoperative detection of submillimeter nodules in an ovarian peritoneal carcinomatosis mouse model.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.119908
Abstract: The epithelial ovarian cancer is one of the most lethal gynecological malignancy due to its late diagnostic and many relapses observed after first line of treatment. Once diagnose, the most important prognostic factor is the… read more here.
Keywords: detection; near infrared; thomsen friedenreich; friedenreich antigen ... See more keywords
Multifunctional nanoprobe based on upconversion nanoparticles for luminescent sensing and magnetic resonance imaging
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Luminescence"
DOI: 10.1016/j.jlumin.2017.05.006
Abstract: Abstract Copper ions (Cu2+) play a key role in ecosystems and human health, however, the copper pollution caused by the excessive use of copper has become one of the main problems of modern world. In… read more here.
Keywords: upconversion nanoparticles; multifunctional nanoprobe; mesoporous silica; magnetic resonance ... See more keywords
Fabrication of G-quadruplex/porphyrin conjugated gold/persistent luminescence theranostic nanoprobe for imaging-guided photodynamic therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122567
Abstract: Photodynamic therapy (PDT) received great attention in cancer therapy due to the advantages of negligible drug resistance, low side effects, and minimal invasiveness. Development of theranostic nanoprobes with specific imaging-guided PDT is of great significance… read more here.
Keywords: imaging guided; porphyrin; pdt; therapy ... See more keywords
In vivo imaging of senescent vascular cells in atherosclerotic mice using a β-galactosidase-activatable nanoprobe.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c02670
Abstract: Senescence-associated diseases have severely diminished the quality of life and health of patients. However, a sensitive assay of these diseases remains limited due to a lack of straightforward methods. Considering that senescence-associated β-galactosidase (SA-β-Gal) is… read more here.
Keywords: activatable nanoprobe; imaging senescent; senescent cells; atherosclerotic mice ... See more keywords
In Situ Detection of Nanotoxicity in Living Cells Based on Multiple miRNAs Probed by a Peptide Functionalized Nanoprobe.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03950
Abstract: The potential toxicity of nanoparticles, especially for clinically applicable ones, has become a critical concern. Technologies that can in situ-evaluate the toxicity of nanoparticles with high sensitivity are urgently needed. In this study, a facile… read more here.
Keywords: multiple mirnas; living cells; detection nanotoxicity; nanotoxicity ... See more keywords
Activatable Nanoprobe with Aggregation-Induced Dual Fluorescence and Photoacoustic Signal Enhancement for Tumor Precision Imaging and Radiotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00340
Abstract: Owing to the high sensitivity and high spatial resolution, fluorescence (FL) imaging has been widely applied for visualizing biological processes. To gain insight into molecular events on deeper tissues, photoacoustic (PA) imaging with better deep-tissue… read more here.
Keywords: activatable nanoprobe; radiotherapy; enhancement; aggregation induced ... See more keywords
Aminopeptidase N Activatable Nanoprobe for Tracking Lymphatic Metastasis and Guiding Tumor Resection Surgery via Optoacoustic/NIR-II Fluorescence Dual-Mode Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01241
Abstract: Lymphatic metastasis is a crucial mechanism by which the cancer cells break away from the primary (original) tumor and travel to the closest regional lymph node(s) and ultimately to other organs or parts of the… read more here.
Keywords: resection surgery; lymphatic metastasis; tumor; nanoprobe ... See more keywords
Water-Dispersible Activatable Nanoprobe for Detecting Cadmium-Ion-Induced Oxidative Stress in Edible Crops via Near-Infrared Second-Window Fluorescence Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03404
Abstract: Edible crops are important in terms of food security and sustainable agriculture. Heavy-metal-ion contamination of water/soil has deleterious impacts on the growth of edible crops. Among the heavy metals, cadmium (Cd) is toxic to plants,… read more here.
Keywords: water; oxidative stress; edible crops; ion ... See more keywords