Interplay between cooperativity of intercellular receptor-ligand binding and coalescence of nanoscale lipid clusters in adhering membranes.
Sign Up to like & getrecommendations! Published in 2021 at "Soft matter"
DOI: 10.1039/d0sm01904f
Abstract: Adhesion of biological cells is mediated by the specific binding of receptors and ligands which are typically large proteins spanning through the plasma membranes of the contacting cells. The receptors and ligands can exhibit affinity… read more here.
Keywords: nanoscale lipid; lipid clusters; receptor ligand; ligand binding ... See more keywords
Engineered Nanoscale Lipid-Based Formulation as Potential Enhancer of Gefitinib Lymphatic Delivery: Cytotoxicity and Apoptotic Studies Against the A549 Cell Line
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02332-7
Abstract: The present study aimed to engineer a nanoscale lipid-based lymphatic drug delivery system with D-α-Tocopherol polyethylene glycol 1000 succinate to combat the lymphatic metastasis of lung cancer. The nanoscale lipid-based systems including GEF-SLN, GEF-NLC, and… read more here.
Keywords: tpgs nlc; gef; gef nlc; gef tpgs ... See more keywords
The chimera of TPGS and Nanoscale Lipid Carriers as Lymphatic Drug Delivery Vehicles to Fight Metastatic Cancers.
Sign Up to like & getrecommendations! Published in 2023 at "Current drug delivery"
DOI: 10.2174/1567201820666230512122825
Abstract: The lymphatic system (LS) plays a crucial role in fluid balance, transportation of macromolecules, and immune response. Moreover, LS is a channel for microbial invasion and cancer metastasis. Particularly, solid tumors, including lung, breast, melanoma,… read more here.
Keywords: lipid carriers; drug delivery; drug; lymphatic drug ... See more keywords