Control of phosphatidylinositol‐3‐kinase signaling by nanoscale membrane compartmentalization
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DOI: 10.1002/bies.202200196
Abstract: Phosphatidylinositol‐3‐kinases (PI3Ks) are lipid kinases that produce 3‐phosphorylated derivatives of phosphatidylinositol upon activation by various cues. These 3‐phosphorylated lipids bind to various protein effectors to control many cellular functions. Lipid phosphatases such as phosphatase and… read more here.
Keywords: control phosphatidylinositol; phosphatidylinositol kinase; nanoscale membrane; membrane ... See more keywords
Nanoscale Membrane Domain Formation Driven by Cholesterol
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DOI: 10.1038/s41598-017-01247-9
Abstract: Biological membranes generate specific functions through compartmentalized regions such as cholesterol-enriched membrane nanodomains that host selected proteins. Despite the biological significance of nanodomains, details on their structure remain elusive. They cannot be observed via microscopic… read more here.
Keywords: membrane domain; domain formation; cholesterol; membrane ... See more keywords