Cryoelectron Tomography Reveals Nanoscale Organization of the Cytoskeleton and Its Relation to Microtubule Curvature Inside Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Structure"
DOI: 10.1016/j.str.2020.05.013
Abstract: Microtubules (MTs) are the most rigid elements of the cytoskeleton with in vitro persistence lengths (Lp) in the range of 1-6 mm. In cellular environments, however, MTs often appear strongly curved. This has been attributed to the… read more here.
Keywords: cytoskeleton; nanoscale organization; organization; curvature ... See more keywords
Asymmetry Between Pre- and Postsynaptic Transient Nanodomains Shapes Neuronal Communication
Sign Up to like & getrecommendations! Published in 2020 at "Trends in Neurosciences"
DOI: 10.1016/j.tins.2020.01.005
Abstract: Synaptic transmission and plasticity are shaped by the dynamic reorganization of signaling molecules within pre- and postsynaptic compartments. The nanoscale organization of key effector molecules has been revealed by single-particle trajectory (SPT) methods. Interestingly, this… read more here.
Keywords: nanoscale organization; postsynaptic transient; asymmetry pre; pre postsynaptic ... See more keywords
Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance
Sign Up to like & getrecommendations! Published in 2017 at "Nature Immunology"
DOI: 10.1038/ni.3813
Abstract: Caveolin-1 (Cav1) regulates the nanoscale organization and compartmentalization of the plasma membrane. Here we found that Cav1 controlled the distribution of nanoclusters of isotype-specific B cell antigen receptors (BCRs) on the surface of B cells.… read more here.
Keywords: bcr; nanoscale organization; caveolin dependent; cav1 ... See more keywords
Real-time nanoscale organization of amyloid precursor protein.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/d0nr00052c
Abstract: Despite an intuitive understanding of the role of APP in health and disease, there exist few attempts to dissect its molecular localization at excitatory synapses. Though the biochemistry involved in the enzymatic processing of APP… read more here.
Keywords: nanoscale organization; app; time nanoscale; real time ... See more keywords
Nanoscale organization of rotavirus replication machineries
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.42906
Abstract: Rotavirus genome replication and assembly take place in cytoplasmic electron dense inclusions termed viroplasms (VPs). Previous conventional optical microscopy studies observing the intracellular distribution of rotavirus proteins and their organization in VPs have lacked molecular-scale… read more here.
Keywords: microscopy; organization; rotavirus; replication ... See more keywords
Regulation of immune receptor kinase plasma membrane nanoscale organization by a plant peptide hormone and its receptors
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.74162
Abstract: Spatial partitioning is a propensity of biological systems orchestrating cell activities in space and time. The dynamic regulation of plasma membrane nano-environments has recently emerged as a key fundamental aspect of plant signaling, but the… read more here.
Keywords: receptor; nanoscale organization; kinase; plasma membrane ... See more keywords