Effective loading of cisplatin into a nanoscale UiO-66 metal-organic framework with preformed defects.
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DOI: 10.1039/c9dt00719a
Abstract: Defects within the nanoscale UiO-66 metal-organic framework (MOF) are created to lock a hybrid phosphonoacetate ligand through Zr-O-P linkages, leaving the carboxyl group free to anchor cisplatin prodrug cis, cis, trans-[Pt(NH3)2Cl2(OH)2]. A drug loading of… read more here.
Keywords: cisplatin; metal organic; nanoscale uio; uio metal ... See more keywords